12789-03-6

12789-03-6结构式
12789-03-6结构式

化源商城直购

中文名 氯丹(技术混合物)
英文名 1,3,4,7,8,9,10,10-Octachlorotricyclo[5.2.1.02,6]dec-8-ene
中文别名 氯丹
密度 1.8g/cm3
沸点 424.7ºC at 760mmHg
熔点 106-107ºC
分子式 C10H6Cl8
分子量 409.77900
闪点 212.5ºC
精确质量 405.79800
LogP 5.68280
蒸汽压 5.02E-07mmHg at 25°C
折射率 1.627
储存条件 库房通风低温干燥,与食品原料分开储运

CHEMICAL IDENTIFICATION

RTECS NUMBER :
FN5955000
CHEMICAL NAME :
Chlordane
CAS REGISTRY NUMBER :
12789-03-6
LAST UPDATED :
199609

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
283 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>1600 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
350 mg/kg/28D-C
TOXIC EFFECTS :
Liver - changes in liver weight Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - other esterases Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - other oxidoreductases
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
DOSE :
880 mg/kg
SEX/DURATION :
female 7-17 day(s) after conception
TOXIC EFFECTS :
Reproductive - Maternal Effects - other effects Reproductive - Specific Developmental Abnormalities - musculoskeletal system
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
DOSE :
144 mg/kg
SEX/DURATION :
female 1-18 day(s) after conception
TOXIC EFFECTS :
Reproductive - Effects on Newborn - biochemical and metabolic

MUTATION DATA

TYPE OF TEST :
Morphological transformation
TEST SYSTEM :
Rodent - hamster Embryo
DOSE/DURATION :
5 mg/L
REFERENCE :
AETODY Advances in Modern Environmental Toxicology. (Senate Press, Inc., P.O. Box 252, Princeton Junction, NJ 08550) V.1- 1980- Volume(issue)/page/year: 1,241,1980 *** REVIEWS *** IARC Cancer Review:Animal Sufficient Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 53,115,1991 IARC Cancer Review:Human Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 53,115,1991 IARC Cancer Review:Group 2B IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 53,115,1991 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 51590 No. of Facilities: 1431 (estimated) No. of Industries: 17 No. of Occupations: 19 No. of Employees: 20937 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 51590 No. of Facilities: 387 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 3833 (estimated) No. of Female Employees: 574 (estimated)

危害码 (欧洲) Xn: Harmful;N: Dangerous for the environment;
风险声明 (欧洲) R21/22
安全声明 (欧洲) 36/37-60-61
危险品运输编码 UN 2810 6.1/PG 3
RTECS号 FN5955000
环戊二烯用氯气氯化,在40-60℃得到四氯环戊烷,进一步加热、通氯,得到多氯环戊烷,将其在汽化釜中气化后与氯气在500-560℃氯解得到六氯环戊二烯。六氯环戊二烯在55℃左右与环戊二烯反应生成氯啶,然后在80℃左右通氯,就得到氯丹