5213-49-0

• 常用中文名：2,4-二硝基咪唑
• 常用英文名：2,4-Dinitro-1H-imidazole
• CAS号：5213-49-0
• 分子式：C₃H₂N₄O₄
• 分子量：158.07200
• 发布时间：2018-04-10 08:00:00
• 更新时间：2025-08-26 13:05:42
• 2，4-二硝基咪唑作为合成中间体单体，广泛应用在医药的合成，人造血浆，抗生素的合成，聚合物材料等领域。

名称

• 中文名: 2,4-二硝基咪唑
• 英文名: 2,5-Dinitro-1H-imidazole
• 中文别名: 2,4-二硝基-1H-咪唑
• 英文别名: Imidazole,2,4-dinitro; Imidazole,2,5-dinitro; KA 121; 2,4-dinitro-1(3)H-imidazole; 2,4-DINITRO-1H-IMIDAZOLE; 2,5-Dinitroimidazole; 2,4-Dinitroimidazole

物化性质

• 密度: 1.867g/cm3
• 沸点: 503.1ºC at 760 mmHg
• 熔点: 263 - 265°C
• 分子式: C₃H₂N₄O₄
• 分子量: 158.07200
• 闪点: 258.1ºC
• 精确质量: 158.00800
• PSA: 120.32000
• LogP: 1.27250
• 外观性状: 浅黄色至明黄色固体
• 折射率: 1.676
• 储存条件: 20°C

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : NI5200000 CHEMICAL NAME : Imidazole, 2,4-dinitro- CAS REGISTRY NUMBER : 5213-49-0 LAST UPDATED : 199712 DATA ITEMS CITED : 2 MOLECULAR FORMULA : C3-H2-N4-O4 MOLECULAR WEIGHT : 158.09 WISWESSER LINE NOTATION : T5M CNJ BNW DNW HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 860 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : RPOBAR Research Progress in Organic-Biological and Medicinal Chemistry. (New York, NY) V.1-3, 1964-72. Discontinued. Volume(issue)/page/year: 2,287,1970 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 465 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : RPOBAR Research Progress in Organic-Biological and Medicinal Chemistry. (New York, NY) V.1-3, 1964-72. Discontinued. Volume(issue)/page/year: 2,287,1970

安全

• 危害码 (欧洲): Xi

合成路线

19182-81-1 ~92% 5213-49-0

文献：Cho, Jin Rai; Kim, Kwang Joo; Cho, Soo Gyeong; Kim, Jeong Kook Journal of Heterocyclic Chemistry, 2002 , vol. 39, # 1 p. 141 - 148

3034-38-6 ~% 5213-49-0

文献：Zwawiak, Justyna; Olender, Dorota; Zwolska, Zofia; Augustynowicz-Kopec, Ewa; Zaprutko, Lucjusz Acta Poloniae Pharmaceutica - Drug Research, 2008 , vol. 65, # 2 p. 229 - 233

19182-81-1 ~1% 3034-38-6 24079-73-0 5213-49-0

文献：Bulusu, S.; Damavarapu, R.; Autera, J. R.; Behrens, R., Jr.; Minier, L. M.; et al. Journal of Physical Chemistry, 1995 , vol. 99, # 14 p. 5009 - 5015

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