3572-41-6

• 常用中文名：N-(5-Isobutyl-1,3,4-thiadiazol-2-yl)-p-toluenesulfonamide
• 常用英文名：N-(5-Isobutyl-1,3,4-thiadiazol-2-yl)-p-toluenesulfonamide
• CAS号：3572-41-6
• 分子式：C₁₃H₁₇N₃O₂S₂
• 分子量：311.42300
• 发布时间：2017-07-30 20:29:57
• 更新时间：2024-02-01 18:40:04

名称

• 英文名: 4-methyl-N-[5-(2-methylpropyl)-1,3,4-thiadiazol-2-yl]benzenesulfonamide
• 英文别名: 5-p-Tolylsulfonylamino-2-isobutyl-1,3,4-thiadiazol; 2-p-Methylbenzenesulfonamido-5-isobutyl-1,3,4-thiadiazole; 5-p-Toluolsulfonylamino-2-isobutyl-1,3,4-thiadiazol; FWH 106

物化性质

• 密度: 1.314g/cm3
• 沸点: 464.7ºC at 760 mmHg
• 分子式: C₁₃H₁₇N₃O₂S₂
• 分子量: 311.42300
• 闪点: 234.8ºC
• 精确质量: 311.07600
• PSA: 108.57000
• LogP: 3.99960
• 折射率: 1.597

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : XT5830000 CHEMICAL NAME : p-Toluenesulfonamide, N-(5-isobutyl-1,3,4-thiadiazol-2-yl)- CAS REGISTRY NUMBER : 3572-41-6 BEILSTEIN REFERENCE NO. : 0271816 LAST UPDATED : 199707 DATA ITEMS CITED : 3 MOLECULAR FORMULA : C13-H17-N3-O2-S2 MOLECULAR WEIGHT : 311.45 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 2400 mg/kg TOXIC EFFECTS : Behavioral - ataxia Endocrine - hypoglycemia Nutritional and Gross Metabolic - body temperature decrease REFERENCE : TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 4,631,1962 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 1650 mg/kg TOXIC EFFECTS : Behavioral - ataxia Endocrine - hypoglycemia Nutritional and Gross Metabolic - body temperature decrease REFERENCE : TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 4,631,1962 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 270 mg/kg TOXIC EFFECTS : Behavioral - ataxia Endocrine - hypoglycemia Nutritional and Gross Metabolic - body temperature decrease REFERENCE : TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 4,631,1962

安全

• 海关编码: 2935009090

合成路线

503-74-2 79-19-6 98-59-9 ~% 3572-41-6

文献：O'Neal,J.B. et al. Journal of Medicinal and Pharmaceutical Chemistry, 1962 , vol. 5, p. 617 - 626

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海关

海关编码	2935009090
中文概述	2935009090 其他磺（酰）胺. 增值税率:17.0% 退税率:9.0% 监管条件:无 最惠国关税:6.5% 普通关税:35.0%
申报要素	品名, 成分含量, 用途
Summary	2935009090 other sulphonamides VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:35.0%