73736-50-2

• 常用中文名：O-去甲基阿司咪唑
• 常用英文名：O-Desmethyl Astemizole
• CAS号：73736-50-2
• 分子式：C₂₇H₂₉FN₄O
• 分子量：444.54400
• 发布时间：2017-06-22 20:18:36
• 更新时间：2026-07-02 18:09:01

名称

• 中文名: O-去甲基阿司咪唑
• 英文名: 4-[2-[4-[[1-[(4-fluorophenyl)methyl]benzimidazol-2-yl]amino]piperidin-1-yl]ethyl]phenol
• 中文别名: 4-(2-(4-((1-(4-氟苄基)-1H-苯并[D]咪唑-2-基)氨基)哌啶-1-基)乙基)苯酚
• 英文别名: Demethylastemizole; O-Desmethyl Astemizole (10mM in DMSO); 4-(2-(4-(1-(4-Fluorobenzyl)-1H-benzo[d]imidazol-2-ylamino)piperidin-1-yl)ethyl)phenol; 4-[2-[4-[[1-(4-Fluorobenzyl)-1H-benzimidazol-2-yl]amino]piperidino]ethyl]phenol; 4-(2-(4-((1-(4-fluorobenzyl)-1H-benzo[d]imidazol-2-yl)amino)piperidin-1-yl)ethyl)phenol; Phenol, 4-(2-(4-((1-((4-fluorophenyl)methyl)-1H-benzimidazol-2-yl)amin o)-1-piperidinyl)ethyl); 4-[2-[4-[1-(4-Fluorobenzyl)-1H-benzoimidazole-2-ylamino]-1-piperidinyl]ethyl]phenol; R 44 271; Desmethylastemizole; DESMETHEYLASTEMIZOLE; 1-(4-fluorobenzyl)-N-(1-(4-(2,2,2-trifluoroethoxy)phenylethyl)piperidin-4-yl)-1H-benzo[d]imidazol-2-amine; O-Demethylastemizole; 4-[2-[4-[[1-[(4-Fluorophenyl)methyl]-1H-benzimidazol-2-yl]amino]-1-piperidinyl]ethyl]phenol; Desmethylasteizole; 4-<2-<4-<<1-<(4-fluorophenyl)methyl>-1H-benzimidazol-2-yl>amino>-1-piperidinyl>ethyl>phenol; Astemizole Impurity 1 (O-Desmethyl Astemizole); [14C]-Desmethylastemizole

物化性质

• 密度: 1.25g/cm3
• 沸点: 644.2ºC at 760 mmHg
• 熔点: 92-94ºC
• 分子式: C₂₇H₂₉FN₄O
• 分子量: 444.54400
• 闪点: 343.4ºC
• 精确质量: 444.23300
• PSA: 53.32000
• LogP: 5.05920
• 折射率: 1.645

合成路线

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