7447-39-4

• 常用中文名：无水氯化铜
• 常用英文名：Cupric chloride
• CAS号：7447-39-4
• 分子式：CuCl₂
• 分子量：134.452
• 相关类别： 无机化工 无机盐 金属卤化物及卤酸盐 金属氯化物及盐
• 发布时间：2018-05-29 08:00:00
• 更新时间：2024-01-02 19:55:34
• 【用途一】
  用作媒染剂、氧化剂、木材防腐剂、食品添加剂、消毒剂等，也用于石油馏分的脱臭和脱硫、金属提炼、照相等

名称

• 中文名: 无水氯化铜
• 英文名: copper(II) chloride
• 中文别名: 氯化铜无水; 氯化铜; 氯化铜(II)
• 英文别名: Cupric chloride; EINECS 231-210-2; copper chloride; Coclor; Copper(2+) dichloride; cupricdichloride; MFCD00010972; Copper(2+) chloride; Copper(2+)chloride; CuCl2; Copper(II) chloride; Cupric dichloride; copper dichloride; copper (ii) chloride; Copper(II) chloride (1:2); Cupperdichloride; copperbichloride

物化性质

• 密度: 3.386 g/mL at 25 °C(lit.)
• 沸点: 993°C/760mmHg
• 熔点: 620 °C(lit.)
• 分子式: CuCl₂
• 分子量: 134.452
• 精确质量: 132.867310
• 外观性状: 棕色或橄榄色至黄褐色的粉末
• 储存条件:

  密封于阴凉干燥环境。

• 稳定性:

  1. 如果遵照规格使用和储存则不会分解。

  2. 无水氯化铜在993℃时分解为氯化亚铜；氯化铜易溶于水及乙醇，也溶于丙酮。

• 水溶解性: 620 g/L (20 ºC)
• 分子结构:

  1、 摩尔折射率：无可用

  2、 摩尔体积（cm³/mol）： 无可用

  3、 等张比容（90.2K）：无可用

  4、 表面张力（dyne/cm）：无可用

  5、 极化率：无可用

• 计算化学:

  1.疏水参数计算参考值（XlogP）:无

  2.氢键供体数量:0

  3.氢键受体数量:0

  4.可旋转化学键数量:0

  5.互变异构体数量:无

  6.拓扑分子极性表面积0

  7.重原子数量:3

  8.表面电荷:0

  9.复杂度:2.8

  10.同位素原子数量:0

  11.确定原子立构中心数量:0

  12.不确定原子立构中心数量:0

  13.确定化学键立构中心数量:0

  14.不确定化学键立构中心数量:0

  15.共价键单元数量:1

• 更多:

  1. 性状：黄色或黄褐色的、具有潮解性的结晶性粉末。

  2. 密度（g/mL,25/4℃）： 3.386

  3. 相对蒸汽密度（g/mL,空气=1）：无可用

  4. 熔点（ºC）：620

  5. 沸点（ºC,常压）：993

  6. 沸点（ºC,5.2kPa）： 无可用

  7. 折射率： 无可用

  8. 闪点（ºC）： 无可用

  9. 比旋光度（º）：无可用

  10. 自燃点或引燃温度（ºC）：无可用

  11. 蒸气压（kPa,25ºC）：无可用

  12. 饱和蒸气压（kPa,60ºC）：无可用

  13. 燃烧热（KJ/mol）：无可用

  14. 临界温度（ºC）：无可用

  15. 临界压力（KPa）：无可用

  16. 油水（辛醇/水）分配系数的对数值：无可用

  17. 爆炸上限（%,V/V）：无可用

  18. 爆炸下限（%,V/V）： 无可用

  19. 溶解性：溶于醇、丙酮和醚。

MSDS

Name: Copper(II) Chloride Anhydrous 98% Material Safety Data Sheet Synonym: Cupric Chloride CAS: 7447-39-4 Section 1 - Chemical Product MSDS Name:Copper(II) Chloride Anhydrous 98% Material Safety Data Sheet Synonym:Cupric Chloride Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS CAS# Chemical Name content EINECS# 7447-39-4 Copper(II) Chloride, Anhydrous, 98% 98% 231-210-2 Hazard Symbols: XN Risk Phrases: 22 36 Section 3 - HAZARDS IDENTIFICATION EMERGENCY OVERVIEW Harmful if swallowed. Irritating to eyes.Hygroscopic (absorbs moisture from the air). Potential Health Effects Eye: Causes eye irritation. May result in corneal injury. Causes redness and pain. Skin: May cause skin irritation. Causes redness and pain. Ingestion: Harmful if swallowed. May cause gastrointestinal irritation with nausea, vomiting and diarrhea. May cause liver and kidney damage. Inhalation: Dust is irritating to the respiratory tract. May cause severe irritation of the upper respiratory tract with pain, burns, and inflammation. May be harmful if inhaled. Chronic: Prolonged or repeated skin contact may cause dermatitis. May cause liver and kidney damage. Section 4 - FIRST AID MEASURES Eyes: Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately. Skin: Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Ingestion: Do not induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid. Inhalation: Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid. Notes to Physician: Section 5 - FIRE FIGHTING MEASURES General Information: Substance is noncombustible. Extinguishing Media: Substance is noncombustible; use agent most appropriate to extinguish surrounding fire. Section 6 - ACCIDENTAL RELEASE MEASURES General Information: Use proper personal protective equipment as indicated in Section 8. Spills/Leaks: Vacuum or sweep up material and place into a suitable disposal container. Clean up spills immediately, observing precautions in the Protective Equipment section. Avoid generating dusty conditions. Provide ventilation. Section 7 - HANDLING and STORAGE Handling: Wash thoroughly after handling. Wash hands before eating. Use only in a well-ventilated area. Minimize dust generation and accumulation. Do not breathe dust, vapor, mist, or gas. Do not get on skin or in eyes. Do not ingest or inhale. Storage: Store in a cool, dry place. Store in a tightly closed container. Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION Engineering Controls: Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate general or local explosion-proof ventilation to keep airborne levels to acceptable levels. Exposure Limits CAS# 7447-39-4: United Kingdom, WEL - TWA: (listed as copper): 0.2 mg/m3 TWA (fum 1 mg/m3 TWA (dust and mist) United Kingdom, WEL - STEL: (listed as copper): 0.6 mg/m3 STEL (fume); 2 mg/m3 STEL (dust and mist) United States OSHA: 0.1 mg/m3 TWA (fume); 1 mg/m3 TWA (dusts and mists) (listed under Copper). Belgium - TWA: (listed as copper): 0.2 mg/m3 VLE (fume); 1 mg/m3 (dust and mist) France - VME: (listed as copper): 0.2 mg/m3 VME (fume); 1 mg/m3 V (dust, as Cu) France - VLE: (listed as copper): 2 mg/m3 VLE (dust, as Cu) Germany: (listed as copper): 0.2 mg/m3 VME (fume); 1 mg/m3 VME (d as Cu) Malaysia: (listed as copper): 0.2 mg/m3 TWA (fume, as Cu); 1 mg/m TWA (dust and mist, as Cu) Netherlands: (listed as copper): 0.2 mg/m3 MAC (smoke); 1 mg/m3 M (dust) Russia: (listed as copper): 1 mg/m3 TWA (dust) Russia: (listed as copper): 0.5 mg/m3 STEL (dust) Spain: (listed as copper): 0.2 mg/m3 VLA-ED (fume); 1 mg/m3 VLA-E (dust and mist, as Cu) Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure. Respirators: Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced. Section 9 - PHYSICAL AND CHEMICAL PROPERTIES Physical State: Crystalline powder Color: brown Odor: Odorless. pH: Not available. Vapor Pressure: Not available. Viscosity: Not available. Boiling Point: 993 deg C @ 760.00mm Hg Freezing/Melting Point: 620 deg C Autoignition Temperature: Not available. Flash Point: Not available. Explosion Limits, lower: Not available. Explosion Limits, upper: Not available. Decomposition Temperature: >300 deg C Solubility in water: soluble Specific Gravity/Density: 3.3860g/cm3 Molecular Formula: Cl2Cu Molecular Weight: 134.45 Section 10 - STABILITY AND REACTIVITY Chemical Stability: Stable under normal temperatures and pressures. Conditions to Avoid: Incompatible materials, dust generation, heating to decomposition, exposure to moist air or water. Incompatibilities with Other Materials: Moisture, alkali metals, potassium, sodium, nitromethane, hydrazine, and sodium hypobromite. Hazardous Decomposition Products: Hydrogen chloride. Hazardous Polymerization: Will not occur. Section 11 - TOXICOLOGICAL INFORMATION RTECS#: CAS# 7447-39-4: GL7000000 LD50/LC50: CAS# 7447-39-4: Oral, mouse: LD50 = 233 mg/kg; Oral, rat: LD50 = 584 mg/kg; Oral, rat: LD50 = 140 mg/kg. Carcinogenicity: Copper(II) Chloride, Anhydrous, 98% - Not listed by ACGIH, IARC, or NTP. Other: See actual entry in RTECS for complete information. Section 12 - ECOLOGICAL INFORMATION Ecotoxicity: Fishtoxicity: Strickleback exposed to 2 mg/l (CuCl2) died within 16-24 hr, and steelhead trout and sockeye salmon died in 12-16 hr. Bridgelip sucker exposed to 3 mg/l died within 12-18 hr. (Macphee, C. et al Fish Toxicity Screening Date 1989, Parts 1 and 2, EPA 560/6-89-001, PB 89-156715, Washington, DC) Invertebrate toxicity: The crab Scylla serrata was exposed to 10, 50 and 100 mg/l (Cu2+) for 14 days. The mortality rates were 60, 100 and 100%, respectively. (Arumugam, M. et al Bull. Environ. Contam. Toxicol. 1987, 39(4), 708-715) Section 13 - DISPOSAL CONSIDERATIONS Dispose of in a manner consistent with federal, state, and local regulations. Section 14 - TRANSPORT INFORMATION IATA Shipping Name: COPPER CHLORIDE Hazard Class: 8 UN Number: 2802 Packing Group: III IMO Shipping Name: COPPER CHLORIDE Hazard Class: 8 UN Number: 2802 Packing Group: III RID/ADR Shipping Name: COPPER CHLORIDE Hazard Class: 8 UN Number: 2802 Packing group: III USA RQ: CAS# 7447-39-4: 10 lb final RQ; 4.54 kg final RQ Section 15 - REGULATORY INFORMATION European/International Regulations European Labeling in Accordance with EC Directives Hazard Symbols: XN Risk Phrases: R 22 Harmful if swallowed. R 36 Irritating to eyes. Safety Phrases: S 26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S 39 Wear eye/face protection. WGK (Water Danger/Protection) CAS# 7447-39-4: 2 Canada CAS# 7447-39-4 is listed on Canada's DSL List. CAS# 7447-39-4 is not listed on Canada's Ingredient Disclosure List. US FEDERAL TSCA CAS# 7447-39-4 is listed on the TSCA inventory. SECTION 16 - ADDITIONAL INFORMATION N/A

毒性和生态

毒理学数据: 1 。 试验方法：腹腔 摄入剂量： 7400微克/千克 测试对象：啮齿动物-鼠 毒性类型：急性 毒性作用：详细的毒副作用没有报告以外的其他致死剂量值 2 。 试验方法：静脉 摄入剂量： 1.75万微克/千克 测试对象：啮齿动物-鼠 毒性类型：急性 毒性作用： 详细的毒副作用没有报告以外的其他致死剂量值 3 。 试验方法：吸入 摄入剂量： 20 ug/m3/26W-I 测试对象：啮齿动物-鼠 毒性类型： MutipleDose 毒性作用： 1.改变白细胞（白血球）计数 2.体内的氯变化 生态学数据: 该物质对环境可能有危害，对水体应给予特别注意。 CHEMICAL IDENTIFICATION RTECS NUMBER : GL7000000 CAS REGISTRY NUMBER : 7447-39-4 LAST UPDATED : 199710 DATA ITEMS CITED : 47 MOLECULAR FORMULA : Cl2-Cu MOLECULAR WEIGHT : 134.44 WISWESSER LINE NOTATION : CU G2 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 584 mg/kg TOXIC EFFECTS : Behavioral - somnolence (general depressed activity) Behavioral - convulsions or effect on seizure threshold TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 14700 ug/kg TOXIC EFFECTS : Behavioral - somnolence (general depressed activity) Behavioral - convulsions or effect on seizure threshold TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 5 mg/kg TOXIC EFFECTS : Behavioral - somnolence (general depressed activity) Behavioral - convulsions or effect on seizure threshold TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 233 mg/kg TOXIC EFFECTS : Behavioral - somnolence (general depressed activity) Behavioral - convulsions or effect on seizure threshold TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 7400 ug/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 17500 ug/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value TYPE OF TEST : TCLo - Lowest published toxic concentration ROUTE OF EXPOSURE : Inhalation SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 20 ug/m3/26W-I TOXIC EFFECTS : Blood - changes in leukocyte (WBC) count Nutritional and Gross Metabolic - changes in chlorine TYPE OF TEST : TCLo - Lowest published toxic concentration ROUTE OF EXPOSURE : Inhalation DOSE : 8 ug/m3 SEX/DURATION : female 1-21 day(s) after conception TOXIC EFFECTS : Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants) Reproductive - Effects on Embryo or Fetus - extra-embryonic structures (e.g., placenta, umbilical cord) Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus) TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Intraperitoneal DOSE : 35 mg/kg SEX/DURATION : female 12-18 day(s) after conception TOXIC EFFECTS : Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants) Reproductive - Effects on Embryo or Fetus - fetal death MUTATION DATA TYPE OF TEST : DNA damage TEST SYSTEM : Mammal - species unspecified Lymphocyte DOSE/DURATION : 2 mmol/L REFERENCE : SCIEAS Science. (American Assoc. for the Advancement of Science, 1333 H St., NW, Washington, DC 20005) V.1- 1895- Volume(issue)/page/year: 198,513,1977 *** REVIEWS *** TOXICOLOGY REVIEW 85DHAX "Medical and Biologic Effects of Environmental Pollutants Series," Washington, DC, National Academy of Sciences, 1972-77 Volume(issue)/page/year: Cu,23,1977 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-ARAB Republic of Egypt:TWA 0.1 mg(Cu)/m3 (fume) JAN 1993 OEL-AUSTRALIA:TWA 0.2 mg(Cu)/m3 (fume) JAN 1993 OEL-AUSTRALIA:TWA 1 mg(Cu)/m3 (dust) JAN 1993 OEL-BELGIUM:TWA 0.2 mg(Cu)/m3 (fume) JAN 1993 OEL-BELGIUM:TWA 1 mg(Cu)/m3 (dust) JAN 1993 OEL-DENMARK:TWA 0.1 mg(Cu)/m3 (fume) JAN 1993 OEL-DENMARK:TWA 1 mg(Cu)/m3 (dust) JAN 1993 OEL-FINLAND:TWA 0.2 mg(Cu)/m3 (fume) JAN 1993 OEL-FINLAND:TWA 1 mg(Cu)/m3 (dust) JAN 1993 OEL-FRANCE:TWA 0.2 mg(Cu)/m3 (fume) JAN 1993 OEL-FRANCE:TWA 1 mg(Cu)/m3;STEL 2 mg(Cu)/m3 (dust) JAN 1993 OEL-GERMANY:TWA 0.1 mg(Cu)/m3 (fume) JAN 1993 OEL-GERMANY:TWA 1 mg(Cu)/m3 (dust) JAN 1993 OEL-HUNGARY:TWA 0.2 mg(Cu)/m3;STEL 0.4 mg(Cu)/m3 (dust) JAN 1993 OEL-INDIA:TWA 0.2 mg(Cu)/m3 (fume) JAN 1993 OEL-THE NETHERLANDS:TWA 02 mg(Cu)/m3 (fume) JAN 1993 OEL-THE NETHERLANDS:TWA 1 mg(Cu)/m3 (dust) JAN 1993 OEL-THE PHILIPPINES:TWA 1.0 mg(Cu)/m3 (fume) JAN 1993 OEL-POLAND:TWA 0.1 mg(Cu)/m3 (fume) JAN 1993 OEL-RUSSIA:STEL 0.5 ppm (1 mg(Cu)/m3) (dust) JAN 1993 OEL-SWEDEN:TWA 0.2 mg(Cu)/m3 (resp. dust) JAN 1993 OEL-SWEDEN:TWA 0.2 mg(Cu)/m3 (fume) JAN 1993 OEL-SWEDEN:TWA 1 mg(Cu)/m3 (total dust) JAN 1993 OEL-SWITZERLAND:TWA 0.1 mg(Cu)/m3;STEL 0.2 mg(Cu)/m3 (fume) JAN 1993 OEL-SWITZERLAND:TWA 1 mg(Cu)/m3;STEL 1 mg(Cu)/m3 JAN 1993 OEL-THAILAND:TWA 0.1 mg(Cu)/m3 (fume) JAN 1993 OEL-THAILAND:TWA 1 mg(Cu)/m3 JAN 1993 OEL-UNITED KINGDOM:TWA 0.2 mg(Cu)/m3 (fume) JAN 1993 OEL-UNITED KINGDOM:TWA 1 mg(Cu)/m3 JAN 1993 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X9857 No. of Facilities: 1154 (estimated) No. of Industries: 20 No. of Occupations: 28 No. of Employees: 16759 (estimated) No. of Female Employees: 9684 (estimated)

安全

• 符号: GHS05, GHS07, GHS09
• 信号词: Danger
• 危害声明: H302 + H312-H315-H318-H410
• 警示性声明: P273-P280-P305 + P351 + P338
• 个人防护装备: dust mask type N95 (US);Eyeshields;Gloves
• 危害码 (欧洲): T:Toxic
• 风险声明 (欧洲): R25;R36/37/38;R50/53
• 安全声明 (欧洲): S61-S57-S45-S37/39-S29-S26-S60-S36
• 危险品运输编码: UN 3264 8/PG 3
• WGK德国: 2
• RTECS号: GL7000000
• 包装等级: III
• 危险类别: 8
• 海关编码: 28274990

合成路线

7782-50-5 12775-96-1 ~% 7447-39-4

文献：Chemical Physics, , vol. 178, p. 505 - 514

制备

1.将纯的二水合氯化铜CuCl2·2H2O用稀盐酸重结晶，以除去其中的碱式盐。然后将其放在干燥的氯化氢气流中，于140～150℃下脱水，直至重量不再减少时为止。将所得无水物置于盛有浓硫酸和氢氧化钠的干燥器中，以除去附着在晶体上的氯化氢。

海关

海关编码	28274990