73987-38-9

• 常用中文名：6-喹啉甲酸乙酯
• 常用英文名：Ethyl quinoline-6-carboxylate
• CAS号：73987-38-9
• 分子式：C₁₂H₁₁NO₂
• 分子量：201.221
• 相关类别： 医药中间体 杂环化合物 喹啉类化合物
• 发布时间：2018-07-11 13:38:38
• 更新时间：2024-01-08 08:00:20

名称

• 中文名: 6-喹啉甲酸乙酯
• 英文名: quinoline-6-carboxylic acid ethyl ester
• 中文别名: 6-喹啉羧酸乙酯
• 英文别名: 6-Quinolinecarboxylic acid, ethyl ester; ethyl quinoline-6-carboxylate

物化性质

• 密度: 1.2±0.1 g/cm3
• 沸点: 328.3±15.0 °C at 760 mmHg
• 分子式: C₁₂H₁₁NO₂
• 分子量: 201.221
• 闪点: 152.4±20.4 °C
• 精确质量: 201.078979
• PSA: 39.19000
• LogP: 2.64
• 蒸汽压: 0.0±0.7 mmHg at 25°C
• 折射率: 1.600
• 储存条件: 室温

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : VB2050000 CHEMICAL NAME : 6-Quinolinecarboxylic acid, ethyl ester CAS REGISTRY NUMBER : 73987-38-9 BEILSTEIN REFERENCE NO. : 0148800 LAST UPDATED : 199712 DATA ITEMS CITED : 1 MOLECULAR FORMULA : C12-H11-N-O2 MOLECULAR WEIGHT : 201.24 WISWESSER LINE NOTATION : T66 BNJ HVO2 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 180 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) Volume(issue)/page/year: NX#02880

安全

• 危害码 (欧洲): Xi
• 海关编码: 2933499090

合成路线

10349-57-2 64-17-5 ~86% 73987-38-9

文献：Lehmann, Thomas; Fischer, Rudiger; Albers, Markus; Rolle, Thomas; Muller, Gerhard; Hessler, Gerhard; Tajimi, Masaomi; Ziegelbauer, Karl; Okigami, Hiromi; Bacon, Kevin; Hasegawa, Haruki Patent: US2003/232868 A1, 2003 ; Location in patent: Page 15-16 ;

101248-36-6 ~68% 73987-38-9

文献：Symeonidis, Theodoros S.; Lykakis, Ioannis N.; Litinas, Konstantinos E. Tetrahedron, 2013 , vol. 69, # 23 p. 4612 - 4616

612-57-7 64-17-5 201230-82-2 ~73% 73987-38-9

文献：Watson, Donald A.; Fan, Xuexiang; Buchwald, Stephen L. Journal of Organic Chemistry, 2008 , vol. 73, # 18 p. 7096 - 7101

150-13-0 ~% 73987-38-9

文献：Journal of the American Chemical Society, , vol. 68, p. 2721

10349-57-2 ~% 73987-38-9

文献：Journal of the American Chemical Society, , vol. 68, p. 2721

海关

海关编码	2933499090
中文概述	2933499090. 其他含喹琳或异喹啉环系的化合物〔但未进一步稠合的〕. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
Summary	2933499090. other compounds containing in the structure a quinoline or isoquinoline ring-system (whether or not hydrogenated), not further fused. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%