14097-40-6

• 常用中文名：2-甲基-1,2,3,4-四氢异喹啉-7-胺
• 常用英文名：2-methyl-1,2,3,4-tetrahydroisoquinolin-7-amine
• CAS号：14097-40-6
• 分子式：C₁₀H₁₄N₂
• 分子量：162.23200
• 发布时间：2018-12-27 09:40:09
• 更新时间：2024-01-20 18:13:52

名称

• 中文名: 1,2,3,4-四氢-2-甲基-7-异喹啉胺
• 英文名: 2-methyl-3,4-dihydro-1H-isoquinolin-7-amine
• 英文别名: 1,2,3,4-TETRAHYDRO-2-METHYL-7-ISOQUINOLINAMINE; 2-methyl-7-amino-1,2,3,4-tetrahydroisoquinoline; 7-Isoquinolinamine,1,2,3,4-tetrahydro-2-methyl; 7-amino-2-methyl-1,2,3,4-tetrahydroisoquinoline; 2-methyl-1,2,3,4-tetrahydro-7-isoquinolinamine; 2-METHYL-1,2,3,4-TETRAHYDROISOQUINOLIN-7-AMINE

物化性质

• 密度: 1.084g/cm3
• 沸点: 290.805ºC at 760 mmHg
• 分子式: C₁₀H₁₄N₂
• 分子量: 162.23200
• 闪点: 113.132ºC
• 精确质量: 162.11600
• PSA: 29.26000
• LogP: 1.77580
• 蒸汽压: 0.002mmHg at 25°C
• 折射率: 1.597
• 储存条件: 2-8°C， 避光， 惰性气体

合成路线

14097-35-9 ~98% 14097-40-6

文献：Chan, Wai N.; Hadley, Michael S.; Harling, John D.; Herdon, Hugh J.; Orlek, Barry S.; Riley, Graham J.; Stead, Rachel E. A.; Stean, Tania O.; Thompson, Mervyn; Upton, Neil; Ward, Robert W. Bioorganic and Medicinal Chemistry, 2000 , vol. 8, # 8 p. 2085 - 2094

171049-41-5 ~97% 14097-40-6

文献：BOEHRINGER INGELHEIM INTERNATIONAL GMBH; BOEHRINGER INGELHEIM PHARMA GMBH and CO. KG Patent: WO2007/48802 A1, 2007 ; Location in patent: Page/Page column 93 ;

42923-79-5 ~% 14097-40-6

文献：Chan, Wai N.; Hadley, Michael S.; Harling, John D.; Herdon, Hugh J.; Orlek, Barry S.; Riley, Graham J.; Stead, Rachel E. A.; Stean, Tania O.; Thompson, Mervyn; Upton, Neil; Ward, Robert W. Bioorganic and Medicinal Chemistry, 2000 , vol. 8, # 8 p. 2085 - 2094

24954-63-0 ~% 14097-40-6

文献：Chan, Wai N.; Hadley, Michael S.; Harling, John D.; Herdon, Hugh J.; Orlek, Barry S.; Riley, Graham J.; Stead, Rachel E. A.; Stean, Tania O.; Thompson, Mervyn; Upton, Neil; Ward, Robert W. Bioorganic and Medicinal Chemistry, 2000 , vol. 8, # 8 p. 2085 - 2094

181514-37-4 ~% 14097-40-6

文献：Chan, Wai N.; Hadley, Michael S.; Harling, John D.; Herdon, Hugh J.; Orlek, Barry S.; Riley, Graham J.; Stead, Rachel E. A.; Stean, Tania O.; Thompson, Mervyn; Upton, Neil; Ward, Robert W. Bioorganic and Medicinal Chemistry, 2000 , vol. 8, # 8 p. 2085 - 2094

99365-69-2 ~% 14097-40-6

文献：ABBOTT LABORATORIES; BA-MAUNG, Nwe Y.; CLARK, Richard F.; ERICKSON, Scott A.; FIDANZE, Steve D.; KAWAI, Megumi; MANTEI, Robert A.; SHEPPARD, George S.; SORENSON, Bryan K.; WANG, Gary T. Patent: WO2011/53476 A1, 2011 ; WO 2011/053476 A1

91-21-4 ~% 14097-40-6

文献：BOEHRINGER INGELHEIM INTERNATIONAL GMBH; COOK, Brian Nicholas; KOWALSKI, Jennifer A.; LI, Xiang; MARSHALL, Daniel Richard; SCHLYER, Sabine; SIBLEY, Robert; SMITH-KEENAN, Lana Louise; SOLEYMANZADEH, Fariba; SORCEK, Ronald John; YOUNG, Erick Richard Roush; ZHANG, Yunlong Patent: WO2012/6203 A1, 2012 ; WO 2012/006203 A1

1612-65-3 ~% 14097-41-7 14097-40-6

文献：Ochiai; Nakagome Chemical and Pharmaceutical Bulletin, 1958 , vol. 6, p. 497,500

108130-11-6 ~% 14097-40-6

文献：Lusinchi et al. Comptes Rendus Hebdomadaires des Seances de l'Academie des Sciences, 1959 , vol. 248, p. 426

上下游产品

上游产品  9
14097-35-9 171049-41-5 42923-79-5 24954-63-0
181514-37-4 99365-69-2 91-21-4 1612-65-3
108130-11-6
下游产品  1
88493-58-7