CHEMICAL IDENTIFICATION
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RTECS NUMBER :
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OQ2290500
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CHEMICAL NAME :
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Maytansine, O(sup 3)-acetyl-O(sup 3)-de(2-(acetylmethylamino)-1-oxopropyl)-22-demethyl-
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CAS REGISTRY NUMBER :
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77353-67-4
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LAST UPDATED :
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199207
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DATA ITEMS CITED :
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2
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MOLECULAR FORMULA :
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C29-H37-Cl-N2-O9
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MOLECULAR WEIGHT :
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593.13
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
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TYPE OF TEST :
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LDLo - Lowest published lethal dose
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ROUTE OF EXPOSURE :
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Intraperitoneal
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SPECIES OBSERVED :
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Rodent - mouse
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DOSE/DURATION :
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2500 ug/kg
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TOXIC EFFECTS :
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Details of toxic effects not reported other than lethal dose value
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REFERENCE :
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EPXXDW European Patent Application. (U.S. Patent and Trademark Office, Foreign Patents, Washington, DC 20231) Volume(issue)/page/year: #25898
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TYPE OF TEST :
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LD - Lethal dose
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ROUTE OF EXPOSURE :
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Intravenous
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SPECIES OBSERVED :
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Rodent - mouse
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DOSE/DURATION :
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>1 gm/kg
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TOXIC EFFECTS :
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Details of toxic effects not reported other than lethal dose value
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REFERENCE :
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JKXXAF Japanese Kokai Tokyo Koho Patents. (U.S. Patent and Trademark Office, Foreign Patents, Washington, DC 20231) Volume(issue)/page/year: #80-118490
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