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77353-67-4

77353-67-4 structure
77353-67-4 structure

Name Antibiotic C 15003PND-1
Synonyms Maytansine,O(sup 3)-acetyl-O(sup 3)-de(2-(acetylmethylamino)-1-oxopropyl)-22-demethyl
Density 1.34g/cm3
Boiling Point 789ºC at 760 mmHg
Molecular Formula C29H37ClN2O9
Molecular Weight 593.06500
Flash Point 431ºC
Exact Mass 592.21900
PSA 151.93000
LogP 3.38830
Index of Refraction 1.592

CHEMICAL IDENTIFICATION

RTECS NUMBER :
OQ2290500
CHEMICAL NAME :
Maytansine, O(sup 3)-acetyl-O(sup 3)-de(2-(acetylmethylamino)-1-oxopropyl)-22-demethyl-
CAS REGISTRY NUMBER :
77353-67-4
LAST UPDATED :
199207
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C29-H37-Cl-N2-O9
MOLECULAR WEIGHT :
593.13

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
2500 ug/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
EPXXDW European Patent Application. (U.S. Patent and Trademark Office, Foreign Patents, Washington, DC 20231) Volume(issue)/page/year: #25898
TYPE OF TEST :
LD - Lethal dose
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>1 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JKXXAF Japanese Kokai Tokyo Koho Patents. (U.S. Patent and Trademark Office, Foreign Patents, Washington, DC 20231) Volume(issue)/page/year: #80-118490