490-55-1

• 常用中文名：阿米苯唑
• 常用英文名：Amiphenazole
• CAS号：490-55-1
• 分子式：C₉H₉N₃S
• 分子量：191.25300
• 发布时间：2018-07-04 22:26:41
• 更新时间：2025-08-21 09:38:35

名称

• 中文名: 阿米苯唑
• 英文名: 5-phenyl-1,3-thiazole-2,4-diamine
• 中文别名: 5-苯基-2,4-噻唑二胺
• 英文别名: 5-phenyl-thiazole-2,4-diyldiamine; Fenamizol; Dizol; Phenamizol; 2,4-diamino-5-phenylthiazole; Amiphenazole; Daptazile; 5-phenyl-thiazole-2,4-diamine; Amifenazol; Phenamizole; Amiphenazol; Daftazol; 5-Phenyl-thiazol-2,4-diyldiamin

物化性质

• 密度: 1.347g/cm3
• 沸点: 413.3ºC at 760mmHg
• 分子式: C₉H₉N₃S
• 分子量: 191.25300
• 闪点: 203.7ºC
• 精确质量: 191.05200
• PSA: 93.17000
• LogP: 3.13690
• 蒸汽压: 4.86E-07mmHg at 25°C
• 折射率: 1.715

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : XJ4020000 CHEMICAL NAME : Thiazole, 2,4-diamino-5-phenyl- CAS REGISTRY NUMBER : 490-55-1 BEILSTEIN REFERENCE NO. : 0157088 LAST UPDATED : 199706 DATA ITEMS CITED : 2 MOLECULAR FORMULA : C9-H9-N3-S MOLECULAR WEIGHT : 191.27 WISWESSER LINE NOTATION : T5N CSJ BZ DR& EZ HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 400 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 23,1125,1973 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 290 mg/kg TOXIC EFFECTS : Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - respiratory obstruction Lungs, Thorax, or Respiration - respiratory stimulation REFERENCE : PCJOAU Pharmaceutical Chemistry Journal (English Translation). Translation of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) No.1- 1967- Volume(issue)/page/year: 7,489,1973

安全

• 海关编码: 2934100090

合成路线

22259-85-4 17356-08-0 ~% 490-55-1

文献：Dodson; Turner Journal of the American Chemical Society, 1951 , vol. 73, p. 4517

22259-83-2 17356-08-0 ~% 490-55-1

文献：Chase; Walker Journal of the Chemical Society, 1955 , p. 4443,4450

5798-79-8 17356-08-0 ~% 490-55-1

文献：Davies et al. Journal of the Chemical Society, 1950 , p. 3491,3494

143-33-9 100-52-7 17356-08-0 ~% 490-55-1

文献：Miryan,N.I. et al. Pharmaceutical Chemistry Journal, 1973 , vol. 7, # 8 p. 489 - 491 Khimiko-Farmatsevticheskii Zhurnal, 1973 , vol. 7, # 8 p. 17 - 20

上下游产品

上游产品  4
22259-85-4 5798-79-8 143-33-9 100-52-7
下游产品  0

海关

海关编码	2934100090
中文概述	2934100090. 结构上含有一个非稠合噻唑环的化合物(不论是否氢化). 增值税率:17.0%. 退税率:9.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途
Summary	2934100090 other compounds containing an unfused thiazole ring (whether or not hydrogenated) in the structure VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0%