490-55-1

490-55-1 structure

Name: Amiphenazole
Chemical Name: 5-phenyl-1,3-thiazole-2,4-diamine
CAS Number: 490-55-1
Molecular Formula: C₉H₉N₃S
Molecular Weight: 191.25300
Create Date: 2018-07-04 22:26:41
Modify Date: 2025-08-21 09:38:35

Name	5-phenyl-1,3-thiazole-2,4-diamine
Synonyms	5-phenyl-thiazole-2,4-diyldiamine Fenamizol Dizol Phenamizol 2,4-diamino-5-phenylthiazole Amiphenazole Daptazile 5-phenyl-thiazole-2,4-diamine Amifenazol Phenamizole Amiphenazol Daftazol 5-Phenyl-thiazol-2,4-diyldiamin

Density	1.347g/cm3
Boiling Point	413.3ºC at 760mmHg
Molecular Formula	C₉H₉N₃S
Molecular Weight	191.25300
Flash Point	203.7ºC
Exact Mass	191.05200
PSA	93.17000
LogP	3.13690
Vapour Pressure	4.86E-07mmHg at 25°C
Index of Refraction	1.715

CHEMICAL IDENTIFICATION

RTECS NUMBER :: XJ4020000

CHEMICAL NAME :: Thiazole, 2,4-diamino-5-phenyl-

CAS REGISTRY NUMBER :: 490-55-1

BEILSTEIN REFERENCE NO. :: 0157088

LAST UPDATED :: 199706

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C9-H9-N3-S

MOLECULAR WEIGHT :: 191.27

WISWESSER LINE NOTATION :: T5N CSJ BZ DR& EZ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 400 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 23,1125,1973

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 290 mg/kg

TOXIC EFFECTS :: Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - respiratory obstruction Lungs, Thorax, or Respiration - respiratory stimulation

REFERENCE :: PCJOAU Pharmaceutical Chemistry Journal (English Translation). Translation of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) No.1- 1967- Volume(issue)/page/year: 7,489,1973

HS Code	2934100090

22259-85-4

17356-08-0

490-55-1

Literature: Dodson; Turner Journal of the American Chemical Society, 1951 , vol. 73, p. 4517

22259-83-2

17356-08-0

490-55-1

Literature: Chase; Walker Journal of the Chemical Society, 1955 , p. 4443,4450

5798-79-8

17356-08-0

490-55-1

Literature: Davies et al. Journal of the Chemical Society, 1950 , p. 3491,3494

143-33-9

100-52-7

17356-08-0

490-55-1

Literature: Miryan,N.I. et al. Pharmaceutical Chemistry Journal, 1973 , vol. 7, # 8 p. 489 - 491 Khimiko-Farmatsevticheskii Zhurnal, 1973 , vol. 7, # 8 p. 17 - 20

Precursor 4
22259-85-4 5798-79-8 143-33-9 100-52-7
DownStream 0

HS Code	2934100090
Summary	2934100090 other compounds containing an unfused thiazole ring (whether or not hydrogenated) in the structure VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0%

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