407-91-0

• 常用中文名：Hexanoic acid,6-[(2,2,2-trifluoroacetyl)amino]-
• 常用英文名：Hexanoic acid,6-[(2,2,2-trifluoroacetyl)amino]-
• CAS号：407-91-0
• 分子式：C₈H₁₂F₃NO₃
• 分子量：227.18100
• 发布时间：2017-08-03 11:45:28
• 更新时间：2025-08-27 10:12:38

名称

• 英文名: 6-[(2,2,2-trifluoroacetyl)amino]hexanoic acid
• 英文别名: 6-(N-Trifluoroacetyl)aminocaproic Acid; 6-[N-(trifluoroacetyl)amino]hexanoic acid; 6-trifluoroacetamidocaproic Acid; 6-(2,2,2-trifluoroacetamido)hexanoic acid; 6-trifluroacetamido-hexanoic acid; 6-(N-(trifluroacetyl)amino)hexanoic acid; 6-(Trifluoroacetamido)hexanoic Acid; N-(Trifluoroacetyl)-6-aminocaproic acid; 6-[(trifluoroacetyl)amino]hexanoic acid

物化性质

• 密度: 1.279g/cm3
• 沸点: 345.3ºC at 760mmHg
• 分子式: C₈H₁₂F₃NO₃
• 分子量: 227.18100
• 闪点: 162.7ºC
• 精确质量: 227.07700
• PSA: 66.40000
• LogP: 1.70080
• 蒸汽压: 1.1E-05mmHg at 25°C
• 折射率: 1.418

合成路线

60-32-2 ~60% 407-91-0

文献：TAMIR BIOTECHNOLOGY LTD. Patent: EP267996 A1, 1988 ;

431-47-0 60-32-2 ~99% 407-91-0

文献：Johns Hopkins University School of Medicine Patent: EP1235851 B1, 2006 ; Location in patent: Page/Page column 53 ;

383-63-1 60-32-2 ~93% 407-91-0

文献：McKeen, Catherine M.; Brown, Lynda J.; Nicol, Jamie T.G.; Mellor, John M.; Brown, Tom Organic and Biomolecular Chemistry, 2003 , vol. 1, # 13 p. 2267 - 2275

222528-74-7 ~% 407-91-0

文献：Kleschyov, Andrei L.; Sen', Vasily; Golubev, Valery; Muennemann, Kerstin; Hinderberger, Dariush; Lackner, Karl J.; Weber, Stefan; Terekhov, Maxim; Schreiber, Laura M.; Muenzel, Thomas European Journal of Medicinal Chemistry, 2012 , vol. 58, p. 265 - 271

383-64-2 60-32-2 ~84% 407-91-0

文献：De Vos; Van Elsen; Bollen Nucleosides and Nucleotides, 1994 , vol. 13, # 10 p. 2245 - 2265

407-25-0 60-32-2 ~74% 407-91-0

文献：Robins, Morris J.; Peng, Yunshan; Damaraju, Vijaya L.; Mowles, Delores; Barron, Geraldine; Tackaberry, Tracey; Young, James D.; Cass, Carol E. Journal of Medicinal Chemistry, 2010 , vol. 53, # 16 p. 6040 - 6053

上下游产品

上游产品  5
60-32-2 431-47-0 383-63-1 383-64-2
407-25-0
下游产品  2
117032-51-6 637330-22-4