5227-68-9

• 常用中文名：6H-Purin-6-one,2-amino-1,9-dihydro-, 7-oxide
• 常用英文名：6H-Purin-6-one,2-amino-1,9-dihydro-, 7-oxide
• CAS号：5227-68-9
• 分子式：C₅H₅N₅O₂
• 分子量：167.12500
• 发布时间：2016-10-20 05:49:25
• 更新时间：2025-08-25 20:52:01

名称

• 英文名: Guanine, N-7-oxide
• 英文别名: guanine 7-oxide; 2-Amino-3,9-dihydro-6H-purin-6-one 7-oxide; 2-Amino-1,9-dihydro-6H-purin-6-one 7-oxide; Antibiotic 3780

物化性质

• 密度: 2.31g/cm3
• 沸点: 603.8ºC at 760mmHg
• 分子式: C₅H₅N₅O₂
• 分子量: 167.12500
• 闪点: 319ºC
• 精确质量: 167.04400
• PSA: 113.28000
• LogP: 0.25540
• 折射率: 2.046

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : MF8585000 CHEMICAL NAME : Guanine 7-N-oxide CAS REGISTRY NUMBER : 5227-68-9 LAST UPDATED : 199712 DATA ITEMS CITED : 3 MOLECULAR FORMULA : C5-H5-N5-O2 MOLECULAR WEIGHT : 167.15 WISWESSER LINE NOTATION : T56 BM DN FVM INJ DO HZ HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 95 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : ADTEAS Advances in Teratology. (New York, NY) V.1-5, 1966-72. Discontinued. Volume(issue)/page/year: 3,181,1968 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 40 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : JANTAJ Journal of Antibiotics. (Japan Antibiotics Research Assoc., 2-20-8 Kamiosaki, Shinagawa-ku, Tokyo, 141, Japan) V.2-5, 1948-52; V.21- 1968- Volume(issue)/page/year: 38,972,1985 ** TUMORIGENIC DATA ** TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 390 mg/kg/26W-I TOXIC EFFECTS : Tumorigenic - neoplastic by RTECS criteria Tumorigenic - tumors at site of application REFERENCE : CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 27,925,1967

安全

• 海关编码: 2933990090

合成路线

112698-48-3 ~88% 5227-68-9

文献：Nohara, Fujio; Nishii, Masahiro; Ogawa, Kazuo; Isono, Kiyoshi; Ubukata, Makoto; et. al Tetrahedron Letters, 1987 , vol. 28, # 12 p. 1287 - 1290

117233-72-4 ~66% 5227-68-9

文献：Ogawa; Nishii; Inagaki; Nohara; Saito; Itaya; Fujii Chemical and Pharmaceutical Bulletin, 1992 , vol. 40, # 2 p. 343 - 350

117233-73-5 ~56% 5227-68-9

文献：Ogawa; Nishii; Inagaki; Nohara; Saito; Itaya; Fujii Chemical and Pharmaceutical Bulletin, 1992 , vol. 40, # 2 p. 343 - 350

112698-43-8 ~% 5227-68-9

文献：Ogawa; Nishii; Inagaki; Nohara; Saito; Itaya; Fujii Chemical and Pharmaceutical Bulletin, 1992 , vol. 40, # 2 p. 343 - 350

117233-76-8 ~% 5227-68-9

文献：Ogawa; Nishii; Inagaki; Nohara; Saito; Itaya; Fujii Chemical and Pharmaceutical Bulletin, 1992 , vol. 40, # 2 p. 343 - 350

117233-74-6 ~% 5227-68-9

文献：Ogawa; Nishii; Inagaki; Nohara; Saito; Itaya; Fujii Chemical and Pharmaceutical Bulletin, 1992 , vol. 40, # 2 p. 343 - 350

上下游产品

上游产品  2
112698-48-3 112698-43-8
下游产品  0

海关

海关编码	2933990090
中文概述	2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%