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2856-75-9生产厂家

2856-75-9价格

2856-75-9

2856-75-9结构式
2856-75-9结构式

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中文名 Modaline硫酸盐
英文名 2-methyl-3-piperidin-1-ylpyrazine,sulfuric acid
英文别名 M 7370
2-Methyl-3-piperidinopyrazine monosulfate
W3207B
Pyrazine,2-methyl-3-piperidino-,sulfate
MODALINE SULFATE
描述 Modaline硫酸盐是MAO抑制剂, 用于治疗抑郁症。
相关类别
沸点 294.2ºC at 760mmHg
分子式 C10H17N3O4S
分子量 275.32500
闪点 131.7ºC
精确质量 275.09400
PSA 112.00000
LogP 2.26830
蒸汽压 0.00165mmHg at 25°C
储存条件 2-8℃

CHEMICAL IDENTIFICATION

RTECS NUMBER :
UQ3850000
CAS REGISTRY NUMBER :
2856-75-9
LAST UPDATED :
199012
DATA ITEMS CITED :
6
MOLECULAR FORMULA :
C10-H15-N3.H2-O4-S
MOLECULAR WEIGHT :
275.36
WISWESSER LINE NOTATION :
T6N DNJ B1 C- AT6KJ &Q &S-O4

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Human
DOSE/DURATION :
51 ug/kg
TOXIC EFFECTS :
Behavioral - toxic psychosis Behavioral - changes in motor activity (specific assay)
REFERENCE :
JNDRAK Journal of New Drugs. (Albany, NY) V.1-6, 1961-66. For publisher information, see JCPCBR. Volume(issue)/page/year: 4,86,1964
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
730 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,265,1972
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
190 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,265,1972
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
780 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,265,1972
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
275 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,265,1972
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
100 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) Volume(issue)/page/year: NX#01635