15372-34-6

• 常用中文名：多依雌酸
• 常用英文名：2-Phenanthrenecarboxylicacid, 1-ethyl-1,2,3,4-tetrahydro-7-methoxy-2-methyl-, (1R,2S)-rel-
• CAS号：15372-34-6
• 分子式：C₁₉H₂₂O₃
• 分子量：298.37600
• 发布时间：2018-04-20 08:00:00
• 更新时间：2025-08-20 23:43:35

名称

• 中文名: 多依雌酸
• 英文名: 2-Phenanthrenecarboxylic acid, 1-ethyl-1,2,3,4-tetrahydro-7-methoxy-2-methyl
• 英文别名: rac-3-Methoxy-16.17-seco-oestrapentaen-(A.B)-saeure-(18); 2-Phenanthrenecarboxylic acid,1-ethyl-1,2,3,4-tetrahydro-7-methoxy-2-methyl-,cis-(.+-.); (+-)-7-Methoxy-2t-methyl-1r-aethyl-1.2.3.4-tetrahydro-phenanthren-carbonsaeure-(2c); Bdda me; 1-Ethyl-7-methoxy-2-methyl-1,2,3,4-tetrahydro-2-phenanthrenecarboxylic acid; (+-)-1c-Aethyl-7-methoxy-2-methyl-1,2,3,4-tetrahydro-phenanthren-2r-carbonsaeure; (+-)-7-Methoxy-2t-methyl-1r-ethyl-1,2,3,4-tetrahydro-phenanthren-carbonsaeure-(2c),'(+-)-O-Methyl-cis-bisdehydrodoisynolsaeure; rac-3-Methoxy-16.17-seco-oestrapentaen-(1.3.5.7.9)-saeure-(18); Dl-cis-bisdehydrodoisynolic acid methyl ether; Doisynoestrol; (+-)-1c-ethyl-7-methoxy-2-methyl-1,2,3,4-tetrahydro-phenanthrene-2r-carboxylic acid

物化性质

• 密度: 1.136g/cm3
• 沸点: 480ºC at 760mmHg
• 分子式: C₁₉H₂₂O₃
• 分子量: 298.37600
• 闪点: 172.4ºC
• 精确质量: 298.15700
• PSA: 46.53000
• LogP: 4.37910
• 蒸汽压: 0mmHg at 25°C
• 折射率: 1.582
• 储存条件: 库房通风低温干燥

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : VS3040000 CHEMICAL NAME : 16,17-Seco-13-alpha-estra-1,3,5,7,9-pentaen-17-oic acid, 3-methoxy-, (+-)- CAS REGISTRY NUMBER : 15372-34-6 LAST UPDATED : 199801 DATA ITEMS CITED : 4 MOLECULAR FORMULA : C19-H22-O3 MOLECULAR WEIGHT : 298.41 WISWESSER LINE NOTATION : L B666&&TJ EO1 K2 LVQ HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral DOSE : 17500 ng/kg SEX/DURATION : female 7 day(s) pre-mating TOXIC EFFECTS : Reproductive - Fertility - female fertility index (e.g. # females pregnant per # sperm positive females; # females pregnant per # females mated) REFERENCE : CCPTAY Contraception. (Geron-X, Inc., POB 1108, Los Altos, CA 94022) V.1- 1970- Volume(issue)/page/year: 3,387,1971 TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral DOSE : 300 ug/kg SEX/DURATION : female 7-9 day(s) after conception TOXIC EFFECTS : Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants) REFERENCE : CCPTAY Contraception. (Geron-X, Inc., POB 1108, Los Altos, CA 94022) V.1- 1970- Volume(issue)/page/year: 3,387,1971 TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral DOSE : 2400 ug/kg SEX/DURATION : female 6 day(s) pre-mating TOXIC EFFECTS : Reproductive - Fertility - female fertility index (e.g. # females pregnant per # sperm positive females; # females pregnant per # females mated) REFERENCE : CCPTAY Contraception. (Geron-X, Inc., POB 1108, Los Altos, CA 94022) V.1- 1970- Volume(issue)/page/year: 4,15,1971 TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral DOSE : 2 mg/kg SEX/DURATION : female 1-6 day(s) after conception TOXIC EFFECTS : Reproductive - Fertility - female fertility index (e.g. # females pregnant per # sperm positive females; # females pregnant per # females mated) REFERENCE : AJOGAH American Journal of Obstetrics and Gynecology. (C.V. Mosby Co., 11830 Westline Industrial Dr., St. Louis, MO 63146) V.1- 1920- Volume(issue)/page/year: 115,101,1973