590424-04-7

• 常用中文名：舒尼替尼中间体3
• 常用英文名：4-[[[2-(Diethylamino)ethyl]amino]carbonyl]-3,5-dimethyl-1H-pyrrole-2-carboxylic acid tert-butyl ester
• CAS号：590424-04-7
• 分子式：C₁₈H₃₁N₃O₃
• 分子量：337.45700
• 相关类别： 原料药 抗肿瘤药 替尼类抗肿瘤药
• 发布时间：2018-09-05 10:16:52
• 更新时间：2024-01-21 17:29:53

名称

• 中文名: N-(2-(二乙基氨基)乙基)-5-甲酰基-2,4-二甲基-1H-吡咯-3-甲酰胺
• 英文名: tert-butyl 4-[2-(diethylamino)ethylcarbamoyl]-3,5-dimethyl-1H-pyrrole-2-carboxylate
• 英文别名: 3,5-dimethyl-1H-pyrrole-2,4-dicarboxylic acid 2-tert-butyl ester 4-(2-diethylamino-ethyl)-amide; t-Butyl 4-({[2-(diethylamino)ethyl]amino}carbonyl)-3,5-dimethyl-1H-pyrrole-2-carboxylate; tert-butyl 4-[[[2-(diethylamino)ethyl]amino]carbonyl]-3,5-dimethyl-1H-pyrrole-2-carboxylate; 4-[[[2-(Diethylamino)ethyl]amino]carbonyl]-3,5-dimethyl-1H-pyrrole-2-carboxylic acid tert-butyl ester

物化性质

• 分子式: C₁₈H₃₁N₃O₃
• 分子量: 337.45700
• 精确质量: 337.23700
• PSA: 74.43000
• LogP: 3.04930
• 储存条件: 室温，干燥密封

合成路线

14352-65-9 590424-03-6 ~74% 590424-04-7

文献：Pharmacia and Upjohn Company LLC Patent: US2006/9510 A1, 2006 ; Location in patent: Page/Page column 16 ;

1694-31-1 ~% 590424-04-7

文献：Wang, Ji-Quan; Miller, Kathy D.; Sledge, George W.; Zheng, Qi-Huang Bioorganic and Medicinal Chemistry Letters, 2005 , vol. 15, # 19 p. 4380 - 4384

100-36-7 ~% 590424-04-7

文献：Manley, Jerad M.; Kalman, Monica J.; Conway, Brian G.; Ball, Cynthia C.; Havens, Jeffrey L.; Vaidyanathan, Rajappa Journal of Organic Chemistry, 2003 , vol. 68, # 16 p. 6447 - 6450

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