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| 中文名 | 高瓜氨酸 |
|---|---|
| 英文名 | L-Homocitrulline |
| 英文别名 |
Lysine, N-(aminocarbonyl)-
EINECS 214-722-0 L-HOMOCITRULLINE 2-Amino-6-(carbamoylamino)hexanoic acid MFCD00038143 N-Carbamoyllysine N6-carbamoyl-Lysine |
| 描述 | L-Homocitrulline通过尿素循环途径获得的homoargininosuccinate代谢成高精氨酸 (homoarginine),L-Homocitrulline的代谢异常会导致赖氨酸尿蛋白不耐受 (LPI)。 |
|---|---|
| 相关类别 | |
| 靶点 |
Human Endogenous Metabolite |
| 参考文献 |
| 密度 | 1.241±0.06 g/cm3 |
|---|---|
| 沸点 | 393.0±42.0 °C at 760 mmHg |
| 熔点 | 211-212 ºC (decomp) |
| 分子式 | C7H15N3O3 |
| 分子量 | 189.212 |
| 闪点 | 191.5±27.9 °C |
| 精确质量 | 189.111343 |
| PSA | 118.44000 |
| LogP | -1.60 |
| 蒸汽压 | 0.0±1.9 mmHg at 25°C |
| 折射率 | 1.525 |
| 储存条件 | 2-8°C |
| 水溶解性 | Soluble (49 g/L) (25 ºC) |
| 分子结构 | 1、 摩尔折射率：46.69 2、 摩尔体积（cm3/mol）：152.3 3、 等张比容（90.2K）：420.9 4、 表面张力（dyne/cm）：58.2 5、 极化率（10-24cm3）：18.51 |
|
Material Safety Data Sheet
Section1. Identification of the substance Product Name: L-Homocitrulline Synonyms: Section2. Hazards identification Harmful by inhalation, in contact with skin, and if swallowed. Section3. Composition/information on ingredients. Ingredient name:L-Homocitrulline CAS number:1190-49-4 Section4. First aid measures Skin contact:Immediately wash skin with copious amounts of water for at least 15 minutes while removing contaminated clothing and shoes. If irritation persists, seek medical attention. Eye contact:Immediately wash skin with copious amounts of water for at least 15 minutes. Assure adequate flushing of the eyes by separating the eyelids with fingers. If irritation persists, seek medical attention. Inhalation:Remove to fresh air. In severe cases or if symptoms persist, seek medical attention. Ingestion:Wash out mouth with copious amounts of water for at least 15 minutes. Seek medical attention. Section5. Fire fighting measures In the event of a fire involving this material, alone or in combination with other materials, use dry powder or carbon dioxide extinguishers. Protective clothing and self-contained breathing apparatus should be worn. Section6. Accidental release measures Personal precautions: Wear suitable personal protective equipment which performs satisfactorily and meets local/state/national standards. Respiratory precaution:Wear approved mask/respirator Hand precaution:Wear suitable gloves/gauntlets Skin protection:Wear suitable protective clothing Eye protection:Wear suitable eye protection Methods for cleaning up: Mix with sand or similar inert absorbent material, sweep up and keep in a tightly closed container for disposal. See section 12. Environmental precautions: Do not allow material to enter drains or water courses. Section7. Handling and storage Handling:This product should be handled only by, or under the close supervision of, those properly qualified in the handling and use of potentially hazardous chemicals, who should take into account the fire, health and chemical hazard data given on this sheet. Store in closed vessels. Storage: Section8. Exposure Controls / Personal protection Engineering Controls: Use only in a chemical fume hood. Personal protective equipment: Wear laboratory clothing, chemical-resistant gloves and safety goggles. General hydiene measures: Wash thoroughly after handling. Wash contaminated clothing before reuse. Section9. Physical and chemical properties Appearance:Not specified Boiling point:No data No data Melting point: Flash point:No data Density:No data Molecular formula:C7H15N3O3 Molecular weight:189.2 Section10. Stability and reactivity Conditions to avoid: Heat, flames and sparks. Materials to avoid: Oxidizing agents. Possible hazardous combustion products: Carbon monoxide, nitrogen oxides. Section11. Toxicological information No data. Section12. Ecological information No data. Section13. Disposal consideration Arrange disposal as special waste, by licensed disposal company, in consultation with local waste disposal authority, in accordance with national and regional regulations. Section14. Transportation information Non-harzardous for air and ground transportation. Section15. Regulatory information No chemicals in this material are subject to the reporting requirements of SARA Title III, Section 302, or have known CAS numbers that exceed the threshold reporting levels established by SARA Title III, Section 313. SECTION 16 - ADDITIONAL INFORMATION N/A |
| 危害码 (欧洲) | Xi |
|---|---|
| 风险声明 (欧洲) | R36/37/38:Irritating to eyes, respiratory system and skin . |
| 安全声明 (欧洲) | S26-S36/37/39 |
| WGK德国 | 3 |
| 海关编码 | 2924199090 |
|
~%
1190-49-4 |
| 文献：Journal of Biological Chemistry, , vol. 180, p. 1253,1258 |
|
~%
1190-49-4 |
| 文献：Journal of the Chemical Society of Pakistan, , vol. 34, # 2 p. 451 - 454 |
| 上游产品 2 | |
|---|---|
| 下游产品 2 | |
| 海关编码 | 2924199090 |
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| 中文概述 | 2924199090. 其他无环酰胺（包括无环氨基甲酸酯)(包括其衍生物及盐）. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:30.0% |
| 申报要素 | 品名, 成分含量, 用途, 包装 |
| Summary | 2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |
