486443-73-6

• 常用中文名：LC3-mHTT-IN-AN1
• 常用英文名：LC3-mHTT-IN-AN1
• CAS号：486443-73-6
• 分子式：C₁₅H₉Br₂NO₃
• 分子量：411.045
• 发布时间：2020-08-11 06:54:26
• 更新时间：2023-02-10 20:34:46
• LC3-mHTT-IN-AN1 (Compound AN1) is a mHTT-LC3 linker compound, which interacts with both mutant huntingtin protein (mHTT) and LC3B but not with wtHTT or irrelevant control proteins. LC3-mHTT-IN-AN1 reduces the levels of mHTT in an allele-selective manner in cultured Huntington disease (HD) mouse neurons.

名称

• 中文名: 5-溴-3-[(3-溴-4,5-二羟基苯基)亚甲基]-1H-吲哚-2-酮
• 英文名: LC3-mHTT-IN-AN1
• 英文别名: (3Z)-5-Bromo-3-(3-bromo-4,5-dihydroxybenzylidene)-1,3-dihydro-2H-indol-2-one; 2H-Indol-2-one, 5-bromo-3-[(3-bromo-4,5-dihydroxyphenyl)methylene]-1,3-dihydro-, (3Z)-

物化性质

• 密度: 2.0±0.1 g/cm3
• 沸点: 586.1±50.0 °C at 760 mmHg
• 分子式: C₁₅H₉Br₂NO₃
• 分子量: 411.045
• 闪点: 308.3±30.1 °C
• 精确质量: 408.894897
• LogP: 5.079
• 蒸汽压: 0.0±1.7 mmHg at 25°C
• 折射率: 1.777
• 储存条件: 2-8°C