68247-53-0
68247-53-0结构式
- 常用中文名：glycoprotein 3-α-L-fucosyltransferase
- 常用英文名：glycoprotein 3-α-L-fucosyltransferase
- CAS号：68247-53-0
- 分子式：
- 分子量：
- 发布时间：2020-04-07 10:51:30
- 更新时间：2025-09-13 22:55:24
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需要Mn2+。该酶转移到N-连接的低聚糖结构(N-聚糖),通常对带有一个未取代的非还原末端GlcNAc残基的N-聚糖具有特异性。这种酶催化的反应类似于酶代码EC2.4.1.68,糖蛋白6-α-L-岩藻糖基转移酶,但将L-岩藻糖基从GDP-β-L-岩藻糖转移到形成α1,3-键而不是α1,6-键。这种酶的N-聚糖产物存在于植物、昆虫和一些其他无脊椎动物(如血吸虫、血吸虫、淋菌)中。 反应：GDP-β-L-fucose + N4-{N-acetyl-β-D-glucosaminyl-(1→2)-α-D-mannosyl-(1→3)-[N-acetyl-β-D-glucosaminyl-(1→2)-α-D-mannosyl-(1→6)]-β-D-mannosyl-(1→4)-N-acetyl-β-D-glucosaminyl-(1→4)-N-acetyl-β-D-glucosaminyl}asparagine = GDP + N4-{N-acetyl-β-D-glucosaminyl-(1→2)-α-D-mannosyl-(1→3)-[N-acetyl-β-D-glucosaminyl-(1→2)-α-D-mannosyl-(1→6)]-β-D-mannosyl-(1→4)-N-acetyl-β-D-glucosaminyl-(1→4)-[α-L-fucosyl-(1→3)]-N-acetyl-β-D-glucosaminyl}asparagine
| 英文名 | glycoprotein 3-α-L-fucosyltransferase |
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| 英文别名 |
EC 2.4.1.214
GDP-L-Fuc:N-acetyl-β-D-glucosaminide α1,3-fucosyltransferase GDP-L-Fuc:Asn-linked GlcNAc α1,3-fucosyltransferase GDP-fucose:β-N-acetylglucosamine (Fuc to (Fucα1→6GlcNAc)-Asn-peptide) α1→3-fucosyltransferase GDP-L-fucose:glycoprotein (L-fucose to asparagine-linked N-acetylglucosamine of 4-N-{N-acetyl-β-D-glucosaminyl-(1→2)-α-D-mannosyl-(1→3)-[N-acetyl-β-D-glucosaminyl-(1→2)-α-D-mannosyl-(1→6)]-β-D-mannosyl-(1→4)-N-acetyl-β-D-glucosaminyl-(1→4)-N-acetyl-β-D-glucosaminyl}asparagine) 3-α-L-fucosyl-transferase GDP-L-fucose:glycoprotein (L-fucose to asparagine-linked N-acetylglucosamine of N4-{N-acetyl-β-D-glucosaminyl-(1→2)-α-D-mannosyl-(1→3)-[N-acetyl-β-D-glucosaminyl-(1→2)-α-D-mannosyl-(1→6)]-β-D-mannosyl-(1→4)-N-acetyl-β-D-glucosaminyl-(1→4)-N-acetyl-β-D-glucosaminyl}asparagine) 3-α-L-fucosyl-transferase |
| 描述 | 需要Mn2+。该酶转移到N-连接的低聚糖结构(N-聚糖),通常对带有一个未取代的非还原末端GlcNAc残基的N-聚糖具有特异性。这种酶催化的反应类似于酶代码EC2.4.1.68,糖蛋白6-α-L-岩藻糖基转移酶,但将L-岩藻糖基从GDP-β-L-岩藻糖转移到形成α1,3-键而不是α1,6-键。这种酶的N-聚糖产物存在于植物、昆虫和一些其他无脊椎动物(如血吸虫、血吸虫、淋菌)中。 反应：GDP-β-L-fucose + N4-{N-acetyl-β-D-glucosaminyl-(1→2)-α-D-mannosyl-(1→3)-[N-acetyl-β-D-glucosaminyl-(1→2)-α-D-mannosyl-(1→6)]-β-D-mannosyl-(1→4)-N-acetyl-β-D-glucosaminyl-(1→4)-N-acetyl-β-D-glucosaminyl}asparagine = GDP + N4-{N-acetyl-β-D-glucosaminyl-(1→2)-α-D-mannosyl-(1→3)-[N-acetyl-β-D-glucosaminyl-(1→2)-α-D-mannosyl-(1→6)]-β-D-mannosyl-(1→4)-N-acetyl-β-D-glucosaminyl-(1→4)-[α-L-fucosyl-(1→3)]-N-acetyl-β-D-glucosaminyl}asparagine |
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| 暂时没有任何物化性质资料 |