78543-08-5

• 常用中文名：Diethyl (4-amino-3-fluorophenyl)methylmalonate
• 常用英文名：Diethyl (4-amino-3-fluorophenyl)methylmalonate
• CAS号：78543-08-5
• 分子式：C₁₄H₁₈FNO₄
• 分子量：283.29500
• 发布时间：2017-01-26 15:36:53
• 更新时间：2024-01-29 19:32:45

名称

• 英文名: diethyl 2-[(4-amino-3-fluorophenyl)methyl]propanedioate

物化性质

• 密度: 1.204g/cm3
• 沸点: 370.1ºC at 760 mmHg
• 分子式: C₁₄H₁₈FNO₄
• 分子量: 283.29500
• 闪点: 177.6ºC
• 精确质量: 283.12200
• PSA: 78.62000
• LogP: 2.27400
• 折射率: 1.518
• 储存条件: 室温

安全

• 危害码 (欧洲): Xn
• 海关编码: 2922499990

合成路线

78543-06-3 ~97% 78543-08-5

文献：GLAXO GROUP LIMITED; ALDER, Catherine, Mary; BALDWIN, Ian, Robert; BARTON, Nicholas, Paul; CAMPBELL, Amanda, Jennifer; CHAMPIGNY, Aurelie, Cecile; HARLING, John, David; MAXWELL, Aoife, Caitriona; SIMPSON, Juliet, Kay; SMITH, Ian, Edward, David; TAME, Christopher, John; WILSON, Caroline; WOOLVEN, James, Michael Patent: WO2010/106016 A1, 2010 ; Location in patent: Page/Page column 117 ; WO 2010/106016 A1

446-35-5 ~% 78543-08-5

文献：Peretto, Ilaria; Radaelli, Stefano; Parini, Carlo; Zandi, Michele; Raveglia, Luca F.; Dondio, Giulio; Fontanella, Laura; Misiano, Paola; Bigogno, Chiara; Rizzi, Andrea; Riccardi, Benedetta; Biscaioli, Marcello; Marchetti, Silvia; Puccini, Paola; Catinella, Silvia; Rondelli, Ivano; Cenacchi, Valentina; Bolzoni, Pier Tonino; Caruso, Paola; Villetti, Gino; Facchinetti, Fabrizio; Del Giudice, Elda; Moretto, Nadia; Imbimbo, Bruno P. Journal of Medicinal Chemistry, 2005 , vol. 48, # 18 p. 5705 - 5720

609-08-5 ~% 78543-08-5

文献：Peretto, Ilaria; Radaelli, Stefano; Parini, Carlo; Zandi, Michele; Raveglia, Luca F.; Dondio, Giulio; Fontanella, Laura; Misiano, Paola; Bigogno, Chiara; Rizzi, Andrea; Riccardi, Benedetta; Biscaioli, Marcello; Marchetti, Silvia; Puccini, Paola; Catinella, Silvia; Rondelli, Ivano; Cenacchi, Valentina; Bolzoni, Pier Tonino; Caruso, Paola; Villetti, Gino; Facchinetti, Fabrizio; Del Giudice, Elda; Moretto, Nadia; Imbimbo, Bruno P. Journal of Medicinal Chemistry, 2005 , vol. 48, # 18 p. 5705 - 5720

上下游产品

上游产品  3
78543-06-3 446-35-5 609-08-5
下游产品  4
52807-12-2 5104-49-4 88975-42-2 88975-89-7

海关

海关编码	2922499990
中文概述	2922499990 其他氨基酸及其酯及它们的盐（含有一种以上含氧基的除外）. 增值税率:17.0% 退税率:9.0% 监管条件:AB(入境货物通关单,出境货物通关单) 最惠国关税:6.5% 普通关税:30.0%
申报要素	品名, 成分含量, 用途, 乙醇胺及其盐应报明色度, 乙醇胺及其盐应报明包装
监管条件	A.入境货物通关单 B.出境货物通关单
检验检疫	P.进境动植物、动植物产品检疫 Q.出境动植物、动植物产品检疫 R.进口食品卫生监督检验 S.出口食品卫生监督检验 M.进口商品检验 N.出口商品检验
Summary	HS:2922499990 other amino-acids, other than those containing more than one kind of oxygen function, and their esters; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:6.5% General tariff:30.0%