54749-86-9

• 常用中文名：噻唑丁炎酮
• 常用英文名：4-butyl-1,2-diphenylpyrazolidine-3,5-dione, compound with 4,5-dihydrothiazol-2-amine (1:1)
• CAS号：54749-86-9
• 分子式：C₂₂H₂₆N₄O₂S
• 分子量：410.53200
• 发布时间：2018-09-02 17:50:27
• 更新时间：2024-02-05 19:41:33

名称

• 中文名: 噻唑丁炎酮
• 英文名: 4-butyl-1,2-diphenylpyrazolidine-3,5-dione,4,5-dihydro-1,3-thiazol-2-amine
• 英文别名: EINECS 259-319-0; 4-Butyl-1,2-diphenyl-3-hydroxy-5-oxo-2-thiazolinyl-2-pyrazolidinium; 2-Thiazoline-2-ammonium-4-n-butyl-1,2-diphenyl-3,5-pyrazolidinedionate; 4,5-dihydro-thiazol-2-ylamine,compound with 4-butyl-1,2-diphenyl-pyrazolidine-3,5-dione (1:1); 4-Butyl-1,2-diphenylpyrazolidine-3,5-dione,compound with 4,5-dihydrothiazol-2-amine (1:1); Thiazolinobutazone; Phenylbutazone salt with 2-amino-2-thiazoline; 3,5-Pyrazolidinedione,4-butyl-1,2-diphenyl-,salt with 2-amino-2-thiazoline; Fordonal; compound with 4,5-dihydrothiazol-2-amine (1:1)

物化性质

• 沸点: 424.9ºC at 760 mmHg
• 分子式: C₂₂H₂₆N₄O₂S
• 分子量: 410.53200
• 闪点: 174.3ºC
• 精确质量: 410.17800
• PSA: 101.80000
• LogP: 4.60390

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : UQ8250000 CHEMICAL NAME : 3,5-Pyrazolidinedione, 4-butyl-1,2-diphenyl-, salt with 2-amino-2-thiazoline CAS REGISTRY NUMBER : 54749-86-9 LAST UPDATED : 197910 DATA ITEMS CITED : 3 MOLECULAR FORMULA : C22-H24-N3-O2-S MOLECULAR WEIGHT : 394.55 WISWESSER LINE NOTATION : T5VNNV EHJ BR& CR& E4 &T5N CS AUTJ BZ HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 1425 mg/kg TOXIC EFFECTS : Gastrointestinal - ulceration or bleeding from stomach REFERENCE : ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 26,1347,1976 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 1650 mg/kg TOXIC EFFECTS : Behavioral - changes in motor activity (specific assay) REFERENCE : ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 26,1347,1976 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 338 mg/kg TOXIC EFFECTS : Behavioral - changes in motor activity (specific assay) REFERENCE : ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 26,1347,1976

合成路线

1779-81-3 50-33-9 ~% 54749-86-9

文献：Moragues; Thiele; Marquez; Colombo; Roberts Arzneimittel-Forschung/Drug Research, 1974 , vol. 24, # 11 p. 1785 - 1786

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