19408-74-3

• 常用中文名：1,2,3,7,8,9-六氯二苯并-对-二恶英
• 常用英文名：1,2,3,7,8,9-Hexachlorodibenzo-p-dioxin
• CAS号：19408-74-3
• 分子式：C₁₂H₂Cl₆O₂
• 分子量：390.86100
• 发布时间：2018-11-28 09:24:45
• 更新时间：2025-08-25 23:15:05

名称

• 中文名: 1,2,3,7,8,9-六氯二苯并-对-二恶英
• 英文名: 1,2,3,7,8,9-Hexachlorodibenzo-p-dioxin
• 英文别名: PCDD 70; 1,2,3,7,8,9-Hexachlorodibenzodioxin; 1,2,3,7,8,9-HxCDD; Dibenzo-p-dioxin,1,2,3,7,8,9-hexachloro; 1,2,3,7,8,9-hexachlorinated dibenzodioxin; 1,2,3,7,8,9-H6CDD; D 70; 1,2,3,7,8,9-hexachlorooxanthrene; 1,2,3,6,7,8,9-hexachloro dibenzo-p-dioxin; HxCDD

物化性质

• 密度: 1.777g/cm3
• 沸点: 478ºC at 760mmHg
• 分子式: C₁₂H₂Cl₆O₂
• 分子量: 390.86100
• 闪点: 182.9ºC
• 精确质量: 387.81900
• PSA: 18.46000
• LogP: 7.50500
• 蒸汽压: 7.72E-09mmHg at 25°C
• 折射率: 1.666
• 计算化学:

  1.疏水参数计算参考值（XlogP）:无

  2.氢键供体数量:0

  3.氢键受体数量:2

  4.可旋转化学键数量:0

  5.互变异构体数量:无

  6.拓扑分子极性表面积:18.5

  7.重原子数量:20

  8.表面电荷:0

  9.复杂度:340

  10.同位素原子数量:0

  11.确定原子立构中心数量:0

  12.不确定原子立构中心数量:0

  13.确定化学键立构中心数量:0

  14.不确定化学键立构中心数量:0

  15.共价键单元数量:1

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : HP3310000 CHEMICAL NAME : Dibenzo-p-dioxin, 1,2,3,7,8,9-hexachloro- CAS REGISTRY NUMBER : 19408-74-3 BEILSTEIN REFERENCE NO. : 1353896 LAST UPDATED : 199806 DATA ITEMS CITED : 9 MOLECULAR FORMULA : C12-H2-Cl6-O2 MOLECULAR WEIGHT : 390.84 WISWESSER LINE NOTATION : T C666 BO IOJ DG EG FG LG MG NG HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : >1440 mg/kg TOXIC EFFECTS : Endocrine - changes in spleen weight Endocrine - changes in thymus weight Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol) TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - guinea pig DOSE/DURATION : 60 ug/kg TOXIC EFFECTS : Nutritional and Gross Metabolic - weight loss or decreased weight gain MUTATION DATA TYPE OF TEST : Morphological transformation TEST SYSTEM : Rodent - mouse Fibroblast DOSE/DURATION : 120 pmol/L REFERENCE : CRNGDP Carcinogenesis (London). (Oxford Univ. Press, Pinkhill House, Southfield Road, Eynsham, Oxford OX8 1JJ, UK) V.1- 1980- Volume(issue)/page/year: 8,1485,1987 *** REVIEWS *** IARC Cancer Review:Animal Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 15,41,1977 IARC Cancer Review:Human No Adequate Data IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 15,41,1977 IARC Cancer Review:Group 3 IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 69,33,1997

安全

• 危险品运输编码: UN 2811
• 包装等级: I
• 危险类别: 6.1(a)
• 海关编码: 2932999060

合成路线

108-90-7 ~% 19408-74-3

文献：Environmental Science and Technology, , vol. 38, # 19 p. 5217 - 5223

127-18-4 ~% 19408-74-3

文献：Environmental Science and Technology, , vol. 37, # 15 p. 3323 - 3331

1746-01-6 ~1% 19408-74-3 35822-46-9 3268-87-9

文献：Analytical Chemistry, , vol. 54, # 3 p. 402 - 406

50563-36-5 ~% 19408-74-3

文献：Chemosphere, , vol. 40, # 2 p. 165 - 175

95-95-4 ~% 19408-74-3 51207-31-9 35822-46-9 详细

文献：Chemosphere, , vol. 45, # 2 p. 129 - 136

58200-74-1 ~% 19408-74-3 57653-85-7

文献：Analytical Chemistry, , vol. 56, # 3 p. 442 - 448

88211-73-8 ~% 19408-74-3 58200-69-4 64461-98-9 详细

文献：Analytical Chemistry, , vol. 56, # 3 p. 442 - 448

50563-36-5 ~% 19408-74-3 3268-87-9 60851-34-5

文献：Chemosphere, , vol. 40, # 2 p. 165 - 175

上下游产品

上游产品  6
108-90-7 127-18-4 1746-01-6 50563-36-5
95-95-4 58200-74-1
下游产品  0

海关

海关编码	2932999060
中文概述	2932999060. 二恶因，呋喃（多氯二苯并对二恶因，多氯二苯并呋喃）. 增值税率:17.0%. 退税率:13.0%. 监管条件:89(禁止出口商品,禁止进口商品). 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途
监管条件	8.禁止出口商品 9.禁止进口商品
Summary	2932999060. Dioxin,Furan(polychorinated dibenzo-p-dioxines,polychlorinated dibenzofurans). VAT:17.0%. Tax rebate rate:13.0%. Supervision conditions:89(articles on the list of prohibited export goods,articles on the list of prohibited import goods). MFN tariff:6.5%. General tariff:20.0%