| 中文名 | 2,6-二氯-9-(四氢-2H-吡喃-2-基)-9h-嘌呤 |
|---|---|
| 英文名 | 2,6-dichloro-9-(oxan-2-yl)purine |
| 中文别名 | 2,5-二溴吡啶 |
| 英文别名 |
2,6-dichloro-9-(tetrahydropyran-2-yl)purine
2,6-dichloro-9-(2-tetrahydropyranyl)-9H-purine 2,6-dichloro-9-(tetrahydropyran-2-yl)-9H-purine 2,6-dichloro-9-(tetrahydro-2h-pyran-2-yl)-9h-purine |
| 密度 | 1.72g/cm3 |
|---|---|
| 沸点 | 417ºC at 760 mmHg |
| 分子式 | C10H10Cl2N4O |
| 分子量 | 273.11900 |
| 闪点 | 206ºC |
| 精确质量 | 272.02300 |
| PSA | 52.83000 |
| LogP | 2.83220 |
| 蒸汽压 | 3.67E-07mmHg at 25°C |
| 折射率 | 1.754 |
| 储存条件 | 2-8°C |
Synonym:None Known Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
Risk Phrases: 22 36/37/38 Section 3 - HAZARDS IDENTIFICATION EMERGENCY OVERVIEW
Harmful if swallowed. Irritating to eyes, respiratory system and skin.The toxicological properties of this material have not been fully investigated. Potential Health Effects Eye: Causes eye irritation. May cause chemical conjunctivitis. Skin: Causes skin irritation. May be harmful if absorbed through the skin. Ingestion: Harmful if swallowed. May cause gastrointestinal irritation with nausea, vomiting and diarrhea. The toxicological properties of this substance have not been fully investigated. Inhalation: Causes respiratory tract irritation. The toxicological properties of this substance have not been fully investigated. May be harmful if inhaled. Chronic: No information found. Section 4 - FIRST AID MEASURES Eyes: Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid. Skin: Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse. Ingestion: Never give anything by mouth to an unconscious person. Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water. Inhalation: Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid. Notes to Physician: Treat symptomatically and supportively. Section 5 - FIRE FIGHTING MEASURES General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Extinguishing Media: Use water spray, dry chemical, carbon dioxide, or appropriate foam. Section 6 - ACCIDENTAL RELEASE MEASURES General Information: Use proper personal protective equipment as indicated in Section 8. Spills/Leaks: Vacuum or sweep up material and place into a suitable disposal container. Clean up spills immediately, observing precautions in the Protective Equipment section. Avoid generating dusty conditions. Provide ventilation. Section 7 - HANDLING and STORAGE Handling: Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. Use with adequate ventilation. Wash clothing before reuse. Storage: Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION Engineering Controls: Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low. Exposure Limits CAS# 20419-68-5: Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure. Respirators: A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant respirator use. Section 9 - PHYSICAL AND CHEMICAL PROPERTIES Physical State: Solid Color: Not available. Odor: Not available. pH: Not available. Vapor Pressure: Not available. Viscosity: Not available. Boiling Point: Not available. Freezing/Melting Point: 191-121 deg C Autoignition Temperature: Not available. Flash Point: Not available. Explosion Limits, lower: Not available. Explosion Limits, upper: Not available. Decomposition Temperature: Solubility in water: Specific Gravity/Density: Molecular Formula: C10H10Cl2N4O Molecular Weight: 273.12 Section 10 - STABILITY AND REACTIVITY Chemical Stability: Stable at room temperature in closed containers under normal storage and handling conditions. Conditions to Avoid: Dust generation. Incompatibilities with Other Materials: Strong oxidizing agents. Hazardous Decomposition Products: Hydrogen chloride, nitrogen oxides, carbon monoxide, carbon dioxide. Hazardous Polymerization: Has not been reported Section 11 - TOXICOLOGICAL INFORMATION RTECS#: CAS# 20419-68-5 unlisted. LD50/LC50: Not available. Carcinogenicity: 2,6-Dichloro-9-(tetrahydro-2H-pyran-2-yl)-9H-purine - Not listed by ACGIH, IARC, or NTP. Section 12 - ECOLOGICAL INFORMATION Section 13 - DISPOSAL CONSIDERATIONS Products which are considered hazardous for supply are classified as Special Waste and the disposal of such chemicals is covered by regulations which may vary according to location. Contact a specialist disposal company or the local waste regulator for advice. Empty containers must be decontaminated before returning for recycling. Section 14 - TRANSPORT INFORMATION IATA Shipping Name: Not Regulated. Hazard Class: UN Number: Packing Group: IMO Shipping Name: Not Regulated. Hazard Class: UN Number: Packing Group: RID/ADR Shipping Name: Not Regulated. Hazard Class: UN Number: Packing group: Section 15 - REGULATORY INFORMATION European/International Regulations European Labeling in Accordance with EC Directives Hazard Symbols: XN Risk Phrases: R 22 Harmful if swallowed. R 36/37/38 Irritating to eyes, respiratory system and skin. Safety Phrases: S 36/37/39 Wear suitable protective clothing, gloves and eye/face protection. S 45 In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible). WGK (Water Danger/Protection) CAS# 20419-68-5: No information available. Canada None of the chemicals in this product are listed on the DSL/NDSL list. CAS# 20419-68-5 is not listed on Canada's Ingredient Disclosure List. US FEDERAL TSCA CAS# 20419-68-5 is not listed on the TSCA inventory. It is for research and development use only. SECTION 16 - ADDITIONAL INFORMATION N/A |
| 海关编码 | 2934999090 |
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|
~88%
20419-68-5 |
| 文献：IRM LLC; THE SCRIPPS RESEARCH INSTITUTE Patent: WO2008/94737 A2, 2008 ; Location in patent: Page/Page column 26-28 ; WO 2008/094737 A2 |
|
~85%
20419-68-5 |
| 文献：Guo, Hai-Ming; Xia, Chao; Niu, Hong-Ying; Zhang, Xiao-Ting; Kong, Si-Nan; Wang, Dong-Chao; Qu, Gui-Rong Advanced Synthesis and Catalysis, 2011 , vol. 353, # 1 p. 53 - 56 |
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| 文献：Mantell, Simon John; Stephenson, Peter Thomas Patent: US2002/72597 A1, 2002 ; |
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20419-68-5 |
| 文献：Pfizer Inc Patent: US6350735 B1, 2002 ; Location in patent: Page column 5-6 ; |
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| 文献：Bhakuni, D. S.; Gupta, P. K.; Chowdhury, B. L. Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1984 , vol. 23, # 12 p. 1286 - 1288 |
| 上游产品 6 | |
|---|---|
| 下游产品 7 | |
| 海关编码 | 2934999090 |
|---|---|
| 中文概述 | 2934999090. 其他杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0% |
| 申报要素 | 品名, 成分含量, 用途 |
| Summary | 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
