Intermolecular Hydrogen Abstraction Reaction between Nitrogen Radicals in Purine Rings and Alkyl Ethers: A Highly Selective Method for the Synthesis of N??9 …

…, HY Niu, XT Zhang, SN Kong, DC Wang…

文献索引：Guo, Hai-Ming; Xia, Chao; Niu, Hong-Ying; Zhang, Xiao-Ting; Kong, Si-Nan; Wang, Dong-Chao; Qu, Gui-Rong Advanced Synthesis and Catalysis, 2011 , vol. 353, # 1 p. 53 - 56

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被引用次数: 29

摘要

Abstract A highly selective method for the synthesis of N-9 alkylated purine nucleoside derivatives via an intermolecular hydrogen abstraction reaction between nitrogen radicals in purine rings and alkyl ethers was developed. Novel purine nucleoside derivatives were obtained with good to high yields in the presence of (diacetoxyiodo) benzene (DIB) and iodine in one-step reaction.