62025-49-4

• 常用中文名：人参皂苷F2
• 常用英文名：Ginsenoside F2
• CAS号：62025-49-4
• 分子式：C₄₂H₇₂O₁₃
• 分子量：785.013
• 相关类别： 生物化工 植物提取物
• 发布时间：2018-04-09 08:00:00
• 更新时间：2026-06-30 17:39:11
• Ginsenoside F2 是Ginsenoside Rb1 的代谢物,可诱导乳腺癌干细胞的凋亡和保护性自噬。

名称

• 中文名: 人参皂苷F2
• 英文名: ginsenoside F2
• 中文别名: 人参皂苷F2对照品; 人参皂苷 F2, 来源于人参; 人参皂甙F2; GINSENOSIDE F2 人参皂苷F2; 人参皂苷F2,10 MM DMSO 溶液; 人参皂苷F2(标准品); (2R,3R,4S,5S,6R)-2-(((3S,5R,8R,9R,10R,12R,13R,14R,17S)-12-羟基-4,4,8,10,14-五甲基-17-((S)-6-甲基-2-(((2S,3R,4S,5S,6R)-3,4,5-三羟基-6-(羟甲基)四氢-2H-吡喃-2-基)氧基)庚-5-烯-2-基)十六氢-1H-环戊并[a]菲-3-基)氧基)-6-(羟甲基)四氢-2H-吡喃-3,4,5-三醇; 人参皂苷F2Ginsenoside F2; 人参皂苷 F2; 人参皂苷-F2
• 英文别名: β-D-Glucopyranoside, (3β,12β)-20-(β-D-glucopyranosyloxy)-12-hydroxydammar-24-en-3-yl; Ginsenoside F2, 10 mM in DMSO; 20(S)-Ginsenoside-F2; (3β,12β)-20-(β-D-Glucopyranosyloxy)-12-hydroxydammar-24-en-3-yl β-D-glucopyranoside; GINSENOSIDE F2; b-D-Glucopyranoside, (3b,12b)-12-hydroxydamm-24-ene-3,20-diyl bis; (2R,3R,4S,5S,6R)-2-(((3S,5R,8R,9R,10R,12R,13R,14R,17S)-12-Hydroxy-4,4,8,10,14-pentamethyl-17-((S)-6-methyl-2-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)ht-5-en-2-yl)hexadecahydro-1H-cyclopenta[a]phenanthren-3-yl)oxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol; (20S)-3β-(β-D-Glucopyranosyloxy)-20-(β-D-glucopyranosyloxy)damm-24-ene-12β-ol; D-glucopyranosidederiv; Ginsenoside F2(AS); Ginsenoside F2 from Panax ginseng C. A. Mey; 12β-Hydroxy-5α-damm-24-ene-3β,20-diylbis(β-D-glucopyranoside); Ginsenoside F2, >=; (2R,3S,4S,5R,6R)-2-(hydroxymethyl)-6-[[(3S,5R,8R,9R,10R,12R,13R,14R,17S)-12-hydroxy-4,4,8,10,14-pentamethyl-17-[(2S)-6-methyl-2-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyht-5-en-2-yl]-2,3,5,6,7,9,11,12,13,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl]oxy]oxane-3,4,5-triol; b-D-Glucopyranoside, (3b,12b)-12-hydroxydamm-24-ene-3,20-d; 20(S)-Ginsenoside F2; β-D-Glucopyranoside, (3β,12β)-12-hydroxydamm-24-ene-3,20-diyl bis; GinsenosideF2; (20S)-3β,20-Bis(β-D-glucopyranosyloxy)-5α-damm-24-ene-12β-ol

物化性质

• 密度: 1.3±0.1 g/cm3
• 沸点: 871.5±65.0 °C at 760 mmHg
• 熔点: 185 °C
• 分子式: C₄₂H₇₂O₁₃
• 分子量: 785.013
• 闪点: 480.9±34.3 °C
• 精确质量: 784.497314
• PSA: 218.99000
• LogP: 3.53
• 外观性状: 固体;White to Almost white powder to crystal
• 蒸汽压: 0.0±0.6 mmHg at 25°C
• 折射率: 1.594
• 储存条件: 0-10°C;避免加热

生物活性

• 描述: Ginsenoside F2 是Ginsenoside Rb1 的代谢物,可诱导乳腺癌干细胞的凋亡和保护性自噬。
• 相关类别:
  信号通路 >> 细胞凋亡 >> 细胞凋亡
  研究领域 >> 癌症
  信号通路 >> 自噬 >> 自噬
• 参考文献:

  [1]. Mai TT, et al. Ginsenoside F2 induces apoptosis accompanied by protective autophagy in breast cancer stem cells. Cancer Lett. 2012 Aug 28;321(2):144-53.

合成路线

6892-79-1 ~% 62025-49-4

文献：Carbohydrate Research, , vol. 177, p. 101 - 110

51116-90-6 ~% 62025-49-4

文献：Carbohydrate Research, , vol. 177, p. 101 - 110

108194-57-6 ~% 62025-49-4

文献：Carbohydrate Research, , vol. 177, p. 101 - 110

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