中文名 | 3,4-二甲氧基-4-氟查尔酮 |
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英文名 | 3,4-dimethoxy-4'-fluorochalcone |
英文别名 | MFCD01901414 |
密度 | 1.182g/cm3 |
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沸点 | 92-94ºC |
熔点 | 90-93ºC(lit.) |
分子式 | C17H15FO3 |
分子量 | 286.29800 |
闪点 | 207.2ºC |
精确质量 | 286.10100 |
PSA | 35.53000 |
LogP | 3.73900 |
蒸汽压 | 1.18E-07mmHg at 25°C |
折射率 | 1.579 |
储存条件 | 密闭于阴凉干燥环境中 |
稳定性 | 遵照规定使用和储存则不会分解。 |
分子结构 | 1、 摩尔折射率:80.45 2、 摩尔体积(m3/mol):242.0 3、 等张比容(90.2K):611.4 4、 表面张力(dyne/cm):40.7 5、 极化率(10-24cm3):31.89 |
计算化学 | 1、 疏水参数计算参考值(XlogP):3.7 2、 氢键供体数量:0 3、 氢键受体数量:4 4、 可旋转化学键数量:5 5、 拓扑分子极性表面积(TPSA):35.5 6、 重原子数量:21 7、 表面电荷:0 8、 复杂度:361 9、 同位素原子数量:0 10、 确定原子立构中心数量:0 11、 不确定原子立构中心数量:0 12、 确定化学键立构中心数量:0 13、 不确定化学键立构中心数量:1 14、 共价键单元数量:1 |
更多 | 1. 性状:无可用 2. 密度(g/mL,25/4℃):无可用 3. 相对蒸汽密度(g/mL,空气=1):无可用 4. 熔点(ºC):132-136 5. 沸点(ºC,常压):无可用 6. 沸点(ºC,5.2kPa):无可用 7. 折射率:无可用 8. 闪点(ºC):无可用 9. 比旋光度(º):无可用 10. 自燃点或引燃温度(ºC):无可用 11. 蒸气压(kPa,25ºC):无可用 12. 饱和蒸气压(kPa,60ºC):无可用 13. 燃烧热(KJ/mol):无可用 14. 临界温度(ºC):无可用 15. 临界压力(KPa):无可用 16. 油水(辛醇/水)分配系数的对数值:无可用 17. 爆炸上限(%,V/V):无可用 18. 爆炸下限(%,V/V):无可用 19. 溶解性:无可用 |
Synonym:1-(4-Fluorophenyl)-3-(3,4-dimethoxyphenyl)-2-propenone Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
Risk Phrases: 36/37/38 Section 3 - HAZARDS IDENTIFICATION EMERGENCY OVERVIEW
Irritating to eyes, respiratory system and skin.The toxicological properties of this material have not been fully investigated. Potential Health Effects Eye: Causes eye irritation. Skin: Causes skin irritation. May be harmful if absorbed through the skin. The toxicological properties of this material have not been fully investigated. Ingestion: May cause irritation of the digestive tract. The toxicological properties of this substance have not been fully investigated. May be harmful if swallowed. Inhalation: Causes respiratory tract irritation. The toxicological properties of this substance have not been fully investigated. May be harmful if inhaled. Chronic: No information found. Section 4 - FIRST AID MEASURES Eyes: In case of contact, immediately flush eyes with plenty of water for at least 15 minutes. Get medical aid. Skin: In case of contact, immediately flush skin with plenty of water. Remove contaminated clothing and shoes. Get medical aid. Wash clothing before reuse. Ingestion: If swallowed, do not induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an unconscious person. Get medical aid. Inhalation: If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid. Notes to Physician: Treat symptomatically and supportively. Section 5 - FIRE FIGHTING MEASURES General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. This material in sufficient quantity and reduced particle size is capable of creating a dust explosion. Extinguishing Media: Use water spray, dry chemical, carbon dioxide, or chemical foam. Section 6 - ACCIDENTAL RELEASE MEASURES General Information: Use proper personal protective equipment as indicated in Section 8. Spills/Leaks: Vacuum or sweep up material and place into a suitable disposal container. Avoid generating dusty conditions. Provide ventilation. Section 7 - HANDLING and STORAGE Handling: Use with adequate ventilation. Minimize dust generation and accumulation. Avoid contact with skin and eyes. Avoid breathing dust. Storage: Store in a cool, dry place. Store in a tightly closed container. Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION Engineering Controls: Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low. Exposure Limits CAS# 28081-14-3: Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure. Respirators: Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced. Section 9 - PHYSICAL AND CHEMICAL PROPERTIES Physical State: Crystalline powder Color: pale yellow Odor: Not available. pH: Not available. Vapor Pressure: Not available. Viscosity: Not available. Boiling Point: 92 - 94 deg C Freezing/Melting Point: 88 - 93 deg C Autoignition Temperature: Not available. Flash Point: Not applicable. Explosion Limits, lower: Not available. Explosion Limits, upper: Not available. Decomposition Temperature: Solubility in water: Insoluble. Specific Gravity/Density: Molecular Formula: C17H15FO3 Molecular Weight: 286.30 Section 10 - STABILITY AND REACTIVITY Chemical Stability: Stable under normal temperatures and pressures. Conditions to Avoid: Dust generation, heat. Incompatibilities with Other Materials: Strong oxidizing agents. Hazardous Decomposition Products: Carbon monoxide, carbon dioxide, hydrogen fluoride gas. Hazardous Polymerization: Will not occur. Section 11 - TOXICOLOGICAL INFORMATION RTECS#: CAS# 28081-14-3 unlisted. LD50/LC50: Not available. Carcinogenicity: 3,4-Dimethoxy-4'-fluorochalcone - Not listed by ACGIH, IARC, or NTP. Section 12 - ECOLOGICAL INFORMATION Section 13 - DISPOSAL CONSIDERATIONS Dispose of in a manner consistent with federal, state, and local regulations. Section 14 - TRANSPORT INFORMATION IATA Not regulated as a hazardous material. IMO Not regulated as a hazardous material. RID/ADR Not regulated as a hazardous material. Section 15 - REGULATORY INFORMATION European/International Regulations European Labeling in Accordance with EC Directives Hazard Symbols: XI Risk Phrases: R 36/37/38 Irritating to eyes, respiratory system and skin. Safety Phrases: S 26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S 37/39 Wear suitable gloves and eye/face protection. WGK (Water Danger/Protection) CAS# 28081-14-3: No information available. Canada None of the chemicals in this product are listed on the DSL/NDSL list. CAS# 28081-14-3 is not listed on Canada's Ingredient Disclosure List. US FEDERAL TSCA CAS# 28081-14-3 is not listed on the TSCA inventory. It is for research and development use only. SECTION 16 - ADDITIONAL INFORMATION N/A |
生态学数据: 该物质对环境可能有危害,对水体应给予特别注意。
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个人防护装备 | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
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危害码 (欧洲) | Xi: Irritant; |
风险声明 (欧洲) | 36/37/38 |
安全声明 (欧洲) | 37/39-26 |
危险品运输编码 | NONH for all modes of transport |
海关编码 | 2914700090 |
~73% 28081-14-3 |
文献:Bansal, R. K.; Mathur, Suchitra; Jain, Jainendra K.; Sharma, Diwakar Journal of the Indian Chemical Society, 1988 , vol. 65, p. 134 - 136 |
~% 28081-14-3 |
文献:Cardia, Maria Cristina; Sanna, Maria Luisa; Meleddu, Rita; Distinto, Simona; Yanez, Matilde; Vina, Dolores; Lamela, Manuel; Maccioni, Elias Journal of Heterocyclic Chemistry, 2013 , vol. 50, # SUPPL.1 p. E87-E92 |
~66% 28081-14-3 |
文献:Bansal, Raj K.; Bhagchandani, Gope Journal fuer Praktische Chemie (Leipzig), 1981 , vol. 323, # 1 p. 49 - 54 |
~% 28081-14-3 |
文献:Bansal, Raj K.; Bhagchandani, Gope Journal fuer Praktische Chemie (Leipzig), 1981 , vol. 323, # 1 p. 49 - 54 |
~% 28081-14-3 |
文献:Bansal, Raj K.; Bhagchandani, Gope Journal fuer Praktische Chemie (Leipzig), 1981 , vol. 323, # 1 p. 49 - 54 |
上游产品 5 | |
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下游产品 0 |
海关编码 | 2914700090 |
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中文概述 | 2914700090 其他酮及醌的卤化、磺化衍生物(包括硝化和亚硝化衍生物). 增值税率:17.0% 退税率:9.0% 监管条件:无 最惠国关税:5.5% 普通关税:30.0% |
申报要素 | 品名, 成分含量, 用途, 丙酮报明包装 |
Summary | HS: 2914700090 halogenated, sulphonated, nitrated or nitrosated derivatives of ketones and quinones, whether or not with other oxygen function Tax rebate rate:9.0% Supervision conditions:none VAT:17.0% MFN tariff:5.5% General tariff:30.0% |