446284-50-0

• 常用中文名：4-氟-1H-吡咯并[2,3-c]吡啶-7-甲腈
• 常用英文名：4-Fluoro-1H-pyrrolo[2,3-c]pyridine-7-carbonitrile
• CAS号：446284-50-0
• 分子式：C₈H₄FN₃
• 分子量：161.136
• 发布时间：2018-12-28 09:51:39
• 更新时间：2025-10-05 14:11:39

名称

• 中文名: 4-氟-1H-吡咯并[2,3-c]吡啶-7-甲腈
• 英文名: 4-fluoro-1H-pyrrolo[2,3-c]pyridine-7-carbonitrile
• 英文别名: 7-cyano-4-fluoro-6-azaindole; 1H-Pyrrolo[2,3-c]pyridine-7-carbonitrile, 4-fluoro-; 4-Fluoro-1H-pyrrolo[2,3-c]pyridine-7-carbonitrile

物化性质

• 密度: 1.4±0.1 g/cm3
• 沸点: 390.9±37.0 °C at 760 mmHg
• 分子式: C₈H₄FN₃
• 分子量: 161.136
• 闪点: 190.2±26.5 °C
• 精确质量: 161.038925
• PSA: 52.47000
• LogP: 0.47
• 蒸汽压: 0.0±0.9 mmHg at 25°C
• 折射率: 1.650

合成路线

446284-38-4 544-92-3 ~65% 446284-50-0

文献：Wang, Tao; Zhang, Zhongxing; Meanwell, Nicholas A.; Kadow, John F.; Yin, Zhiwei; Xue, Qiufen May; Regueiro-Ren, Alicia; Matiskella, John D.; Ueda, Yasutsugu Patent: US2004/110785 A1, 2004 ; Location in patent: Page 79-80 ;

6628-77-9 ~% 446284-50-0

文献：Regueiro-Ren, Alicia; Xue, Qiufen M.; Swidorski, Jacob J.; Gong, Yi-Fei; Mathew, Marina; Parker, Dawn D.; Yang, Zheng; Eggers, Betsy; D'Arienzo, Celia; Sun, Yongnian; Malinowski, Jacek; Gao, Qi; Wu, Dedong; Langley, David R.; Colonno, Richard J.; Chien, Caly; Grasela, Dennis M.; Zheng, Ming; Lin, Pin-Fang; Meanwell, Nicholas A.; Kadow, John F. Journal of Medicinal Chemistry, 2013 , vol. 56, # 4 p. 1656 - 1669

51173-04-7 ~% 446284-50-0

文献：Regueiro-Ren, Alicia; Xue, Qiufen M.; Swidorski, Jacob J.; Gong, Yi-Fei; Mathew, Marina; Parker, Dawn D.; Yang, Zheng; Eggers, Betsy; D'Arienzo, Celia; Sun, Yongnian; Malinowski, Jacek; Gao, Qi; Wu, Dedong; Langley, David R.; Colonno, Richard J.; Chien, Caly; Grasela, Dennis M.; Zheng, Ming; Lin, Pin-Fang; Meanwell, Nicholas A.; Kadow, John F. Journal of Medicinal Chemistry, 2013 , vol. 56, # 4 p. 1656 - 1669

51173-05-8 ~% 446284-50-0

文献：Regueiro-Ren, Alicia; Xue, Qiufen M.; Swidorski, Jacob J.; Gong, Yi-Fei; Mathew, Marina; Parker, Dawn D.; Yang, Zheng; Eggers, Betsy; D'Arienzo, Celia; Sun, Yongnian; Malinowski, Jacek; Gao, Qi; Wu, Dedong; Langley, David R.; Colonno, Richard J.; Chien, Caly; Grasela, Dennis M.; Zheng, Ming; Lin, Pin-Fang; Meanwell, Nicholas A.; Kadow, John F. Journal of Medicinal Chemistry, 2013 , vol. 56, # 4 p. 1656 - 1669

136888-20-5 ~% 446284-50-0

文献：Regueiro-Ren, Alicia; Xue, Qiufen M.; Swidorski, Jacob J.; Gong, Yi-Fei; Mathew, Marina; Parker, Dawn D.; Yang, Zheng; Eggers, Betsy; D'Arienzo, Celia; Sun, Yongnian; Malinowski, Jacek; Gao, Qi; Wu, Dedong; Langley, David R.; Colonno, Richard J.; Chien, Caly; Grasela, Dennis M.; Zheng, Ming; Lin, Pin-Fang; Meanwell, Nicholas A.; Kadow, John F. Journal of Medicinal Chemistry, 2013 , vol. 56, # 4 p. 1656 - 1669

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