446284-38-4

• 常用中文名：7-溴-4-氟-1H-吡咯并[2,3-c]吡啶
• 常用英文名：7-Bromo-4-fluoro-1H-pyrrolo[2,3-c]pyridine
• CAS号：446284-38-4
• 分子式：C₇H₄BrFN₂
• 分子量：215.023
• 发布时间：2018-12-29 22:31:28
• 更新时间：2025-09-12 14:10:52

名称

• 中文名: 7-溴-4-氟-1H-吡咯并[2,3-c]吡啶
• 英文名: 7-Bromo-4-fluoro-1H-pyrrolo[2,3-c]pyridine
• 英文别名: 7-BROMO-4-FLUORO-6-AZAINDOLE; 1H-Pyrrolo[2,3-c]pyridine, 7-bromo-4-fluoro-; 7-Bromo-4-fluoro-1H-pyrrolo[2,3-c]pyridine; 4-fluoro-7-bromo-6-azaindole

物化性质

• 密度: 1.9±0.1 g/cm3
• 沸点: 339.1±37.0 °C at 760 mmHg
• 分子式: C₇H₄BrFN₂
• 分子量: 215.023
• 闪点: 158.9±26.5 °C
• 精确质量: 213.954178
• PSA: 28.68000
• LogP: 1.43
• 蒸汽压: 0.0±0.7 mmHg at 25°C
• 折射率: 1.693
• 储存条件: 室温

合成路线

652160-72-0 1826-67-1 ~35% 446284-38-4

文献：Ueda, Yasutsugu; Connolly, Timothy P.; Kadow, John F.; Meanwell, Nicholas A.; Wang, Tao; Chen, Chung-Pin H.; Yeung, Kap-Sun; Zhang, Zhongxing; Leahy, David Kenneth; Pack, Shawn K.; Soundararajan, Nachimuthu; Sirard, Pierre; Levesque, Kathia; Thoraval, Dominique Patent: US2005/209246 A1, 2005 ; Location in patent: Page/Page column 32 ;

6628-77-9 ~% 446284-38-4

文献：Regueiro-Ren, Alicia; Xue, Qiufen M.; Swidorski, Jacob J.; Gong, Yi-Fei; Mathew, Marina; Parker, Dawn D.; Yang, Zheng; Eggers, Betsy; D'Arienzo, Celia; Sun, Yongnian; Malinowski, Jacek; Gao, Qi; Wu, Dedong; Langley, David R.; Colonno, Richard J.; Chien, Caly; Grasela, Dennis M.; Zheng, Ming; Lin, Pin-Fang; Meanwell, Nicholas A.; Kadow, John F. Journal of Medicinal Chemistry, 2013 , vol. 56, # 4 p. 1656 - 1669

51173-04-7 ~% 446284-38-4

文献：Regueiro-Ren, Alicia; Xue, Qiufen M.; Swidorski, Jacob J.; Gong, Yi-Fei; Mathew, Marina; Parker, Dawn D.; Yang, Zheng; Eggers, Betsy; D'Arienzo, Celia; Sun, Yongnian; Malinowski, Jacek; Gao, Qi; Wu, Dedong; Langley, David R.; Colonno, Richard J.; Chien, Caly; Grasela, Dennis M.; Zheng, Ming; Lin, Pin-Fang; Meanwell, Nicholas A.; Kadow, John F. Journal of Medicinal Chemistry, 2013 , vol. 56, # 4 p. 1656 - 1669

51173-05-8 ~% 446284-38-4

文献：Regueiro-Ren, Alicia; Xue, Qiufen M.; Swidorski, Jacob J.; Gong, Yi-Fei; Mathew, Marina; Parker, Dawn D.; Yang, Zheng; Eggers, Betsy; D'Arienzo, Celia; Sun, Yongnian; Malinowski, Jacek; Gao, Qi; Wu, Dedong; Langley, David R.; Colonno, Richard J.; Chien, Caly; Grasela, Dennis M.; Zheng, Ming; Lin, Pin-Fang; Meanwell, Nicholas A.; Kadow, John F. Journal of Medicinal Chemistry, 2013 , vol. 56, # 4 p. 1656 - 1669

1826-67-1 136888-20-5 ~34% 446284-38-4

文献：Regueiro-Ren, Alicia; Xue, Qiufen M.; Swidorski, Jacob J.; Gong, Yi-Fei; Mathew, Marina; Parker, Dawn D.; Yang, Zheng; Eggers, Betsy; D'Arienzo, Celia; Sun, Yongnian; Malinowski, Jacek; Gao, Qi; Wu, Dedong; Langley, David R.; Colonno, Richard J.; Chien, Caly; Grasela, Dennis M.; Zheng, Ming; Lin, Pin-Fang; Meanwell, Nicholas A.; Kadow, John F. Journal of Medicinal Chemistry, 2013 , vol. 56, # 4 p. 1656 - 1669