116162-74-4

• 常用中文名：1-tert-butyl-6-fluoro-4-oxo-7-piperazin-1-ylquinoline-3-carboxylic acid
• 常用英文名：1-tert-butyl-6-fluoro-4-oxo-7-piperazin-1-ylquinoline-3-carboxylic acid
• CAS号：116162-74-4
• 分子式：C₁₈H₂₂FN₃O₃
• 分子量：347.38400
• 发布时间：2016-11-28 21:20:26
• 更新时间：2025-08-26 23:09:55

名称

• 英文名: 1-tert-butyl-6-fluoro-4-oxo-7-piperazin-1-ylquinoline-3-carboxylic acid

物化性质

• 密度: 1.305g/cm3
• 沸点: 553.7ºC at 760mmHg
• 分子式: C₁₈H₂₂FN₃O₃
• 分子量: 347.38400
• 闪点: 288.7ºC
• 精确质量: 347.16500
• PSA: 74.57000
• LogP: 2.39720
• 蒸汽压: 4.27E-13mmHg at 25°C
• 折射率: 1.588

合成路线

110-85-0 116163-13-4 ~68% 116162-74-4

文献：Bouzard, D.; Cesare, P. Di; Essiz, M.; Jacquet, J. P.; Remuzon, P.; et al. Journal of Medicinal Chemistry, 1989 , vol. 32, # 3 p. 537 - 542

116163-44-1 ~% 116162-74-4

文献：Bouzard, D.; Cesare, P. Di; Essiz, M.; Jacquet, J. P.; Remuzon, P.; et al. Journal of Medicinal Chemistry, 1989 , vol. 32, # 3 p. 537 - 542

86483-52-5 ~% 116162-74-4

文献：Bouzard, D.; Cesare, P. Di; Essiz, M.; Jacquet, J. P.; Remuzon, P.; et al. Journal of Medicinal Chemistry, 1989 , vol. 32, # 3 p. 537 - 542

116163-40-7 ~% 116162-74-4

文献：Bouzard, D.; Cesare, P. Di; Essiz, M.; Jacquet, J. P.; Remuzon, P.; et al. Journal of Medicinal Chemistry, 1989 , vol. 32, # 3 p. 537 - 542

367-21-5 ~% 116162-74-4

文献：Shindikar, Anand V.; Viswanathan Bioorganic and Medicinal Chemistry Letters, 2005 , vol. 15, # 7 p. 1803 - 1806

70032-30-3 ~% 116162-74-4

文献：Shindikar, Anand V.; Viswanathan Bioorganic and Medicinal Chemistry Letters, 2005 , vol. 15, # 7 p. 1803 - 1806

75073-15-3 ~% 116162-74-4

文献：Shindikar, Anand V.; Viswanathan Bioorganic and Medicinal Chemistry Letters, 2005 , vol. 15, # 7 p. 1803 - 1806

上下游产品

上游产品  7
110-85-0 116163-13-4 116163-44-1 86483-52-5
116163-40-7 367-21-5 70032-30-3
下游产品  0