67630-00-6

• 常用中文名：(S)-2-((叔丁氧羰基)氨基)-3-(4-硝基苯基)丙酸乙酯
• 常用英文名：(S)-ethyl 2-(tert-butoxycarbonylamino)-3-(4-nitrophenyl)propanoate
• CAS号：67630-00-6
• 分子式：C₁₆H₂₂N₂O₆
• 分子量：338.35600
• 发布时间：2017-08-21 11:15:05
• 更新时间：2024-01-08 20:44:46

名称

• 中文名: (S)-2-((叔丁氧羰基)氨基)-3-(4-硝基苯基)丙酸乙酯
• 英文名: Ethyl N-{[(2-methyl-2-propanyl)oxy]carbonyl}-4-nitro-L-phenylalan inate
• 英文别名: N-tert-butoxycarbonyl-4-nitro-L-phenylalanine ethyl ester; (S)-2-((tert-butoxycarbonyl)amino)-3-(4-fluorophenyl)propanoic acid; Boc-L-Phe(4-F)-OH; 4-azido-N-[(1,1-dimethylethoxy)carbonyl]-L-phenylalanine; boc-Phe(4-F)-OH; Boc-DL-Phg-OH; N-(tert-butoxycarbonyl)-4-fluoro-L-phenylalanine; N-Boc-4-nitro-L-phenylalanine ethyl ester; Boc-Phe(4-NO2)-OEt; (S)-3-(4-azido-phenyl)-2-tert-butoxycarbonylamino-propionic acid; Boc-Phe(4-N3)-OH; Boc-3-(4-nitro-phenyl)-2-tert-butoxycarbonylamino-propionic acid ethyl ester; 2-[(tert-butoxycarbonyl)amino]-3-(4-fluorophenyl)propanoic acid; N-(tert-butyloxycarbonyl)-4-nitro-L-phenylalanine ethyl ester; N-t-butoxycarbonyl-DL-4-nitrophenylalanine ethyl ester; Boc-P-Fluoro-Dl-Phe-Oh; 4-azido-N-Boc-phenylalanine; tert-Butyloxycarbonyl-4-azido-L-phenylalanin; Boc-Phe(NO2)-OEt; N-Boc-L-p-azidophenylalanine; BOC-d-4-Fluorophenylalanine

物化性质

• 密度: 1.198±0.06 g/cm3
• 沸点: 481.9±40.0℃ at 760 mmHg
• 分子式: C₁₆H₂₂N₂O₆
• 分子量: 338.35600
• 精确质量: 338.14800
• PSA: 113.94000
• LogP: 3.32130
• 储存条件: 室温

合成路线

24424-99-5 ~99% 67630-00-6

文献：MERCK and CO., INC. Patent: WO2006/115918 A2, 2006 ; Location in patent: Page/Page column 17-18 ;

24424-99-5 58816-66-3 ~78% 67630-00-6

文献：Kupczyk-Subotkowska, Lidia; Siahaan, Teruna J.; Basile, Anthony S.; Friedman, Henry S.; Higgins, Patricia E.; Song, Di; Gallo, James M. Journal of Medicinal Chemistry, 1997 , vol. 40, # 11 p. 1726 - 1730

64-17-5 33305-77-0 ~% 67630-00-6

文献：Ajinomoto Co., Inc. Patent: EP1454898 A1, 2004 ; Location in patent: Page 39; 40 ;

74-96-4 33305-77-0 ~83% 67630-00-6

文献：Sasaki; Akutsu; Matsui; Suzuki; Sakurada; Sato; Kisara Chemical and Pharmaceutical Bulletin, 1982 , vol. 30, # 12 p. 4435 - 4443

上下游产品

上游产品  5
24424-99-5 58816-66-3 64-17-5 33305-77-0
74-96-4
下游产品  1
67630-01-7