22766-68-3

• 常用中文名：奎宁环-4-羧酸乙酯
• 常用英文名：Ethyl quinuclidine-4-carboxylate
• CAS号：22766-68-3
• 分子式：C₁₀H₁₇NO₂
• 分子量：183.247
• 发布时间：2017-07-23 09:06:36
• 更新时间：2024-01-20 18:05:17

名称

• 中文名: 乙基奎宁环-4-羧酸酯
• 英文名: Ethyl quinuclidine-4-carboxylate
• 英文别名: 4-Quinuclidinecarboxylic acid,ethyl ester; 1-aza-bicyclo[2.2.2]octane-4-carboxylic acid ethyl ester; 4-Quinuclidinecarboxylic acid, ethyl ester; 4-carbethoxyquinuclidine; 1-Azabicyclo[2.2.2]octane-4-carboxylic acid, ethyl ester; Chinuclidin-4-carbonsaeure-aethylester; ethyl 1-azabicyclo[2.2.2]octane-4-carboxylate; quinuclidine-4-carboxylic acid ethyl ester; ethyl 1-aza-bicyclo[2.2.2]octane-4-carboxylate; Ethyl quinuclidine-4-carboxylate

物化性质

• 密度: 1.1±0.1 g/cm3
• 沸点: 233.4±40.0 °C at 760 mmHg
• 分子式: C₁₀H₁₇NO₂
• 分子量: 183.247
• 闪点: 85.5±18.2 °C
• 精确质量: 183.125931
• PSA: 29.54000
• LogP: 1.38
• 蒸汽压: 0.1±0.5 mmHg at 25°C
• 折射率: 1.511
• 储存条件: 2-8°C

安全

• 危害码 (欧洲): Xi
• 海关编码: 2933990090

合成路线

869112-14-1 ~94% 22766-68-3

文献：Laine, Dramane I.; McCleland, Brent; Thomas, Sonia; Neipp, Christopher; Underwood, Brian; Dufour, Jeremy; Widdowson, Katherine L.; Palovich, Michael R.; Blaney, Frank E.; Foley, James J.; Webb, Edward F.; Luttmann, Mark A.; Burman, Miriam; Belmonte, Kristen; Salmon, Michael Journal of Medicinal Chemistry, 2009 , vol. 52, # 8 p. 2493 - 2505

1276088-72-2 ~% 22766-68-3

文献：GLAXO GROUP LIMITED; CARANGIO, Antonella; CHEUNG, Izabel; D'SOUZA, Erin Carmen Frances; LEAHY, John Henry; STRACHAN, John Bryce Patent: WO2011/29896 A1, 2011 ; Location in patent: Page/Page column 19 ;

142851-03-4 ~% 22766-68-3

文献：GLAXO GROUP LIMITED; CARANGIO, Antonella; CHEUNG, Izabel; D'SOUZA, Erin Carmen Frances; LEAHY, John Henry; STRACHAN, John Bryce Patent: WO2011/29896 A1, 2011 ;

上下游产品

上游产品  2
869112-14-1 142851-03-4
下游产品  3
26608-58-2 45651-41-0 461648-39-5

海关

海关编码	2933990090
中文概述	2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%