77497-74-6

• 常用中文名：(S)-1,2,3,4-四氢-3-异喹啉羧酸叔丁酯盐酸盐
• 常用英文名：(S)-1,2,3,4-TETRAHYDRO-3-ISOQUINOLINECARBOXYLIC ACIDT-BUTYL ESTER
• CAS号：77497-74-6
• 分子式：C₁₄H₂₀ClNO₂
• 分子量：269.767
• 发布时间：2018-12-27 15:56:01
• 更新时间：2025-08-23 10:51:11

名称

• 中文名: (S)-1,2,3,4-四氢-3-异喹啉羧酸叔丁酯盐酸盐
• 英文名: tert-butyl (3S)-1,2,3,4-tetrahydroisoquinoline-3-carboxylate
• 中文别名: (S)-1,2,3,4-四氢-3-异喹啉羧酸叔丁酯
• 英文别名: (S)-1,2,3,4-TETRAHYDRO-3-ISOQUINOLINECARBOXYLIC ACID TERT-BUTYL ESTER; 2-Methyl-2-propanyl (3R)-1,2,3,4-tetrahydro-3-isoquinolinecarboxylate hydrochloride (1:1); (3S)-1,2,3,4-tetrahydro-isoquinoline-3-carboxylic acid tert-butyl ester; TERT-BUTYL (S)-1,2,3,4-TETRAHYDRO-ISOQUINOLINE-3-CARBOXYLATE; THIQ tert-butyl ester; (S)-1,2,3,4-tetrahydro-3-isoquinolinecarboxylic acid,1,1-dimethylethyl ester; 3-Isoquinolinecarboxylic acid, 1,2,3,4-tetrahydro-, 1,1-dimethylethyl ester, (3R)-, hydrochloride (1:1); (S)-1,2,3,4-TETRAHYDRO-3-ISOQUINOLINECARBOXYLIC ACID T-BUTYL ESTER; tert.-butyl (3S)-1,2,3,4-tetrahydroisoquinoline-3-carboxylate

物化性质

• 密度: 1.063 g/cm3
• 沸点: 331.626ºC at 760 mmHg
• 分子式: C₁₄H₂₀ClNO₂
• 分子量: 269.767
• 闪点: 154.362ºC
• 精确质量: 269.118256
• PSA: 38.33000
• LogP: 3.17340
• 外观性状: 白色或者灰色固体
• 折射率: 1.54
• 储存条件: 2-8°C

安全

• 海关编码: 2933499090

合成路线

79276-06-5 ~% 77497-74-6

文献：US2004/192613 A1, ; Page/Page column 5 ;

79276-05-4 ~76% 77497-74-6

文献：Salvadori, Severe; Balboni, Gianfranco; Guerrini, Remo; Tomatis, Roberto; Bianchi, Clementina; Bryant, Sharon D.; Cooper, Peter S.; Lazarus, Lawrence H. Journal of Medicinal Chemistry, 1997 , vol. 40, # 19 p. 3100 - 3108

74163-81-8 ~% 77497-74-6

文献：Journal of Medicinal Chemistry, , vol. 40, # 19 p. 3100 - 3108

79261-58-8 ~% 77497-74-6

文献：Journal of Medicinal Chemistry, , vol. 40, # 19 p. 3100 - 3108

77497-95-1 115-11-7 ~74% 77497-74-6

文献：Hayashi; Ozaki; Nunami; Uchida; Kato; Kinashi; Yoneda Chemical and Pharmaceutical Bulletin, 1983 , vol. 31, # 2 p. 570 - 576

74163-81-8 115-11-7 ~% 77497-74-6

文献：Journal of Medicinal Chemistry, , vol. 29, # 10 p. 1953 - 1961

上下游产品

上游产品  6
79276-06-5 79276-05-4 74163-81-8 79261-58-8
77497-95-1 115-11-7
下游产品  2
85441-61-8 103733-49-9

海关

海关编码	2933499090
中文概述	2933499090. 其他含喹琳或异喹啉环系的化合物〔但未进一步稠合的〕. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
Summary	2933499090. other compounds containing in the structure a quinoline or isoquinoline ring-system (whether or not hydrogenated), not further fused. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%