1174020-40-6

• 常用中文名：(3S,4R)-叔-丁基 3-氟-4-羟基哌啶-1-羧酸酯
• 常用英文名：tert-butyl (3S,4R)-3-fluoro-4-hydroxypiperidine-1-carboxylate
• CAS号：1174020-40-6
• 分子式：C₁₀H₁₈FNO₃
• 分子量：219.253
• 发布时间：2018-12-18 07:22:32
• 更新时间：2024-01-08 14:24:15

名称

• 中文名: (3S,4R)-3-氟-4-羟基哌啶-1-羧酸叔丁酯
• 英文名: (3S,4R)-tert-Butyl 3-fluoro-4-hydroxypiperidine-1-carboxylate
• 中文别名: 3S,4R)-3-氟-4-羟基哌啶-1-羧酸叔丁酯
• 英文别名: 2-Methyl-2-propanyl (3S,4R)-3-fluoro-4-hydroxy-1-piperidinecarboxylate; (3S,4R)-N-t-butyl-4-(2,4-difluorophenyl)pyrrolidine-3-carboxylic acid; 1-Boc-3S-fluoro-4R-piperidinol; 1-Piperidinecarboxylic acid, 3-fluoro-4-hydroxy-, 1,1-dimethylethyl ester, (3S,4R)-; 1-tert-butyl-4-(2,4-difluorophenyl)pyrrolidine-3-carboxylic acid; (3S,4R)-1-tert-butyl-4-(2,4-difluorophenyl)-pyrrolidine-3-carboxylic acid; tert-butyl cis-3-fluoro-4-hydroxy-piperidine-1-carboxylate; (3S,4R)-N-tert-butyl-4-(2,4-difluoro-phenyl)-pyrrolidine-3-carboxylic acid; (cis)-3-fluoro-4-hydroxypiperidine-1-carboxylic acid tert-butyl ester; (3S,4R)-1-t-butyl-4-(2,4-difluorophenyl)pyrrolidine-3-carboxylic acid; tert-butyl (3,4-cis)-3-fluoro-4-hydroxypiperidine-1-carboxylate; tert-butyl (3S,4R)-3-fluoro-4-hydroxypiperidine-1-carboxylate

物化性质

• 密度: 1.2±0.1 g/cm3
• 沸点: 300.8±42.0 °C at 760 mmHg
• 分子式: C₁₀H₁₈FNO₃
• 分子量: 219.253
• 闪点: 135.7±27.9 °C
• 精确质量: 219.127075
• PSA: 49.77000
• LogP: 0.57
• 蒸汽压: 0.0±1.4 mmHg at 25°C
• 折射率: 1.478
• 储存条件: 室温，干燥

安全

• 海关编码: 2933399090

合成路线

1450879-67-0 ~76% 1174020-40-6

文献：Shaw, Simon J.; Goff, Dane A.; Boralsky, Luke A.; Irving, Mark; Singh, Rajinder Journal of Organic Chemistry, 2013 , vol. 78, # 17 p. 8892 - 8897

211108-50-8 ~% 1174020-40-6 1174020-42-8

文献：PFIZER INC.; GUIMARAES, Cristiano Ruch Werneck; MASCITTI, Vincent; MCCLURE, Kim Francis; MUNCHHOF, Michael John; ROBINSON, Ralph Pelton, Jr. Patent: WO2011/36576 A1, 2011 ; WO 2011/036576 A1

211108-48-4 ~% 1174020-40-6 1174020-42-8

文献：PFIZER INC.; GUIMARAES, Cristiano Ruch Werneck; MASCITTI, Vincent; MCCLURE, Kim Francis; MUNCHHOF, Michael John; ROBINSON, Ralph Pelton, Jr. Patent: WO2011/36576 A1, 2011 ; WO 2011/036576 A1

79099-07-3 ~% 1174020-40-6 1174020-42-8

文献：PFIZER INC.; GUIMARAES, Cristiano Ruch Werneck; MASCITTI, Vincent; MCCLURE, Kim Francis; MUNCHHOF, Michael John; ROBINSON, Ralph Pelton, Jr. Patent: WO2011/36576 A1, 2011 ; WO 2011/036576 A1

1208864-35-0 ~% 1174020-40-6 1174020-42-8

文献：PFIZER INC.; MASCITTI, Vincent; MCCLURE, Kim Francis; MUNCHHOF, Michael John; ROBINSON, Ralph Pelton Patent: WO2011/61679 A1, 2011 ; WO 2011/061679 A1

79099-07-3 ~% 1174020-40-6

文献：Shaw, Simon J.; Goff, Dane A.; Boralsky, Luke A.; Irving, Mark; Singh, Rajinder Journal of Organic Chemistry, 2013 , vol. 78, # 17 p. 8892 - 8897

上下游产品

上游产品  5
1450879-67-0 211108-50-8 211108-48-4 79099-07-3
1208864-35-0
下游产品  0

海关

海关编码	2933399090
中文概述	2933399090. 其他结构含非稠合吡啶环的化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
Summary	2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%