124-85-6

• 常用中文名：Pregn-2-en-20-yn-17-ol,acetate, (5a,17a)- (9CI)
• 常用英文名：Pregn-2-en-20-yn-17-ol,acetate, (5a,17a)- (9CI)
• CAS号：124-85-6
• 分子式：C₂₃H₃₂O₂
• 分子量：340.49900
• 发布时间：2016-03-20 12:21:08
• 更新时间：2023-06-20 13:10:27

名称

• 英文名: [(8R,9S,10S,13S,14S)-17-ethynyl-10,13-dimethyl-1,4,5,6,7,8,9,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-17-yl] acetate
• 英文别名: 17-ethynylandrost-2-ene-17-ol-17-acetate

物化性质

• 密度: 1.07g/cm3
• 沸点: 405.6ºC at 760mmHg
• 分子式: C₂₃H₃₂O₂
• 分子量: 340.49900
• 闪点: 171.1ºC
• 精确质量: 340.24000
• PSA: 26.30000
• LogP: 5.13030
• 蒸汽压: 8.64E-07mmHg at 25°C
• 折射率: 1.544
• 分子结构:

  1、 摩尔折射率：99.83

  2、 摩尔体积（cm³/mol）：316.7

  3、 等张比容（90.2K）：806.3

  4、 表面张力（dyne/cm）：41.9

  5、 极化率（10-24cm3）：39.57

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : TU5568500 CHEMICAL NAME : 5-alpha,17-alpha-Pregn-2-en-20-yn-17-ol, acetate CAS REGISTRY NUMBER : 124-85-6 LAST UPDATED : 199403 DATA ITEMS CITED : 8 MOLECULAR FORMULA : C23-H32-O2 MOLECULAR WEIGHT : 340.55 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD - Lethal dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : >2 gm/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : MDACAP Medicamentos de Actualidad. (J.R. Prous, S.A., Apartado de Correos 540, 08080 Barcelona, Spain) V.1- 1965- Volume(issue)/page/year: 23,187,1987 TYPE OF TEST : LD - Lethal dose ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - rat DOSE/DURATION : >2 gm/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : MDACAP Medicamentos de Actualidad. (J.R. Prous, S.A., Apartado de Correos 540, 08080 Barcelona, Spain) V.1- 1965- Volume(issue)/page/year: 23,187,1987 TYPE OF TEST : LD - Lethal dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : >2 gm/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : MDACAP Medicamentos de Actualidad. (J.R. Prous, S.A., Apartado de Correos 540, 08080 Barcelona, Spain) V.1- 1965- Volume(issue)/page/year: 23,187,1987 TYPE OF TEST : LD - Lethal dose ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : >2 gm/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : MDACAP Medicamentos de Actualidad. (J.R. Prous, S.A., Apartado de Correos 540, 08080 Barcelona, Spain) V.1- 1965- Volume(issue)/page/year: 23,187,1987 ** REPRODUCTIVE DATA ** TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral DOSE : 15600 ug/kg SEX/DURATION : female 13 day(s) pre-mating TOXIC EFFECTS : Reproductive - Maternal Effects - ovaries, fallopian tubes REFERENCE : ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 36,1069,1986 TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral DOSE : 15500 ug/kg SEX/DURATION : female 16-20 day(s) after conception TOXIC EFFECTS : Reproductive - Specific Developmental Abnormalities - urogenital system REFERENCE : ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 36,1069,1986 TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral DOSE : 46800 ug/kg SEX/DURATION : male 13 day(s) pre-mating TOXIC EFFECTS : Reproductive - Paternal Effects - testes, epididymis, sperm duct REFERENCE : ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 36,1069,1986 TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Subcutaneous DOSE : 46800 ug/kg SEX/DURATION : female 13 day(s) pre-mating TOXIC EFFECTS : Reproductive - Maternal Effects - ovaries, fallopian tubes REFERENCE : ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 36,1069,1986