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550-34-5

550-34-5结构式
550-34-5结构式

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英文名 2-(diethylamino)ethyl 4-aminonaphthalene-1-carboxylate,hydrochloride
英文别名 4-Amino-[1]naphthoesaeure-(2-diaethylamino-aethylester),Hydrochlorid
1-NAPHTHOIC ACID,4-AMINO-,2-(DIETHYLAMINO)ETHYL ESTER,HYDROCHLORIDE
UNII-96O81DVX5M
4-amino-[1]naphthoic acid-(2-diethylamino-ethyl ester),hydrochloride
Naphthocaine hydrochloride
Naphthacaine hydrochloride
Naphthocaine HCl
密度 1.129g/cm3
沸点 462.2ºC at 760 mmHg
分子式 C17H23ClN2O2
分子量 322.83000
闪点 233.3ºC
精确质量 322.14500
PSA 55.56000
LogP 4.30380
折射率 1.602

CHEMICAL IDENTIFICATION

RTECS NUMBER :
QL1421000
CHEMICAL NAME :
1-Naphthoic acid, 4-amino-, 2-(diethylamino)ethyl ester, hydrochloride
CAS REGISTRY NUMBER :
550-34-5
LAST UPDATED :
199709
DATA ITEMS CITED :
3
MOLECULAR FORMULA :
C17-H22-N2-O2.Cl-H
MOLECULAR WEIGHT :
322.87

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
118 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 94,299,1948
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
107 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold Gastrointestinal - changes in structure or function of salivary glands
REFERENCE :
JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 70,315,1940
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
54 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold Behavioral - muscle contraction or spasticity Gastrointestinal - changes in structure or function of salivary glands
REFERENCE :
JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 70,315,1940

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