4004-95-9

• 常用中文名：1-苯基哌嗪双盐酸盐
• 常用英文名：1-phenylpiperazin-1-ium chloride
• CAS号：4004-95-9
• 分子式：C₁₀H₁₅ClN₂
• 分子量：198.693
• 发布时间：2018-09-27 18:19:47
• 更新时间：2025-08-24 11:37:14

名称

• 中文名: 1-苯基哌嗪双盐酸盐
• 英文名: 1-phenylpiperazine,dihydrochloride
• 中文别名: 1-苯基哌嗪二盐酸盐
• 英文别名: EINECS 223-654-0; Phenobolin hydrochloride; N-PHENYLPIPERAZINE DI-HCL; 1-Phenylpiperazine HCl; Piperazine, 1-phenyl-, hydrochloride (1:1); 4-phenylpiperazine hydrochloride; Piperazine, 1-phenyl-, monohydrochloride; 1-Phenylpiperazine hydrochloride (1:1); N-PHENYLPIPERAZINE DIHYDROCHLORIDE; phenylpiperazine hydrochloride; 1-phenylpiperazine dihydrochloride; 1-phenylpiperazine hydrochloride; 1-phenylpiperazin-1-ium chloride; N-phenyl-piperazine hydrochloride

物化性质

• 沸点: 287.2ºC at 760 mmHg
• 分子式: C₁₀H₁₅ClN₂
• 分子量: 198.693
• 闪点: 138.3ºC
• 精确质量: 198.092377
• PSA: 15.27000
• LogP: 2.29200
• 蒸汽压: 0.00252mmHg at 25°C

安全

• 风险声明 (欧洲): R20/21/22;R36/37/38
• 安全声明 (欧洲): S26-S36/37/39

合成路线

77278-63-8 ~96% 4004-95-9

文献：Salituro, Francesco G.; Saunders, Jeffrey O.; Yan, Shunqi Patent: US2010/331307 A1, 2010 ; Location in patent: Page/Page column 23 ; US 20100331307 A1

821-48-7 74497-02-2 ~73% 4004-95-9

文献：Weng, Zhiyong; Gao, Yanping; Zhang, Jiankang; Dong, Xiaowu; Liu, Tao Journal of Chemical Research, 2011 , vol. 35, # 1 p. 43 - 46

108-86-1 ~% 4004-95-9

文献：AGIOS PHARMACEUTICALS, INC.; SALITURO, Francesco, G.; SAUNDERS, Jeffrey, O. Patent: WO2011/72174 A1, 2011 ; WO 2011/072174 A1

14426-21-2 137-04-2 ~% 4004-95-9

文献：Baiocchi Farmaco, Edizione Scientifica, 1988 , vol. 43, # 12 SUPPL. p. 1053 - 1062

上下游产品

上游产品  5
77278-63-8 821-48-7 108-86-1 14426-21-2
137-04-2
下游产品  4
92-54-6 14761-39-8 57498-25-6 39819-27-7