中文名 | DL-苯丙醇胺盐酸盐 |
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英文名 | DL-Norephedrine hydrochloride |
中文别名 | 盐酸苯丙醇胺 |
英文别名 |
NOREPHEDRINE HCL
α-(1-Aminoethyl)benzyl alcohol hydrochloride a-Hydroxy-b-aminopropylbenzene Hydrochloride dl-NOREPHEDRINE HCl mucorama α-Hydroxy-β-aminopropylbenzene hydrochloride propadrinehydrochloride obestat Benzenemethanol, α-(1-aminoethyl)-, hydrochloride (1:1) a-(1-Aminoethyl)benzyl Alcohol Hydrochloride monydrin DL-1-Phenyl-2-amino-1-propanol monohydrochloride 2-Amino-1-phenyl-1-propanol hydrochloride (1:1) PHENYLPROPANOLAMINE HCL 1-Phenyl-2-amino-1-propanol Hydrochloride LincomycinHydrocloride Phenylpropanolamine hydrochloride 2-Amino-1-phenyl-1-propanol Hydrochloride Benzyl alcohol, α-(1-aminoethyl)-, hydrochloride, (±)- 2-amino-1-phenylpropan-1-ol hydrochloride EINECS 205-826-7 MFCD00013019 benzenemethanol, α-(1-aminoethyl)-, hydrochloride Phenyl propanolamine hydrochloride 2-amino-1-phenyl-1-propanol monohydrochloride 2-Amino-1-phenylpropan-1-ol hydrochloride (1:1) (±)-2-Amino-1-phenyl-1-propanol hydrochloride |
密度 | 1.071 g/cm3 |
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沸点 | 288.1ºC at 760 mmHg |
熔点 | 194-196 °C(lit.) |
分子式 | C9H14ClNO |
分子量 | 187.667 |
闪点 | 128.1ºC |
精确质量 | 187.076385 |
PSA | 46.25000 |
LogP | 2.56950 |
外观性状 | 白色粉末 |
蒸汽压 | 0.0011mmHg at 25°C |
折射率 | 1.557 |
储存条件 | 密封储存,储存于阴凉、干燥的库房。 |
稳定性 | 常温常压下稳定,与强氧化剂反应。 |
计算化学 | 1、 疏水参数计算参考值(XlogP): 2、 氢键供体数量:3 3、 氢键受体数量:2 4、 可旋转化学键数量:2 5、 互变异构体数量: 6、 拓扑分子极性表面积(TPSA):46.3 7、 重原子数量:12 8、 表面电荷:0 9、 复杂度:110 10、同位素原子数量:0 11、确定原子立构中心数量:2 12、不确定原子立构中心数量:0 13、确定化学键立构中心数量:0 14、不确定化学键立构中心数量:0 15、共价键单元数量:2 |
更多 | 1. 性状:白色苦味结晶状粉末 2. 密度(g/mL, 25 ℃ ):1.25 3. 相对蒸汽密度(g/mL,空气=1):未确定 4. 熔点(ºC):194-196 5. 沸点(ºC,常压):255 6. 沸点(ºC,3mmHg):未确定 7. 折射率(n20/D):未确定 8. 闪点(ºF):未确定 9. 比旋光度(º):未确定 10. 自燃点或引燃温度(ºC):未确定 11. 蒸气压(mmHg,20ºC):未确定 12. 饱和蒸气压(kPa,83-85ºC):未确定 13. 燃烧热(KJ/mol):未确定 14. 临界温度(ºC):未确定 15. 临界压力(KPa):未确定 16. 油水(辛醇/水)分配系数的对数值:未确定 17. 爆炸上限(%,V/V):未确定 18. 爆炸下限(%,V/V):未确定 19. 溶解性:溶于水和醇,不溶于醚、氯仿和苯 |
Synonym:alpha-(1-Aminoethyl)benzyl alcohol hydrochloride; DL-Phenylpropanolamine hydrochloride ; Alpha-hydroxy-beta-Aminopropylbenzene Hydrochloride; Propadrine Hydrochloride Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
Risk Phrases: 22 Section 3 - HAZARDS IDENTIFICATION EMERGENCY OVERVIEW
Harmful if swallowed.Light sensitive. Potential Health Effects Eye: May cause eye irritation. Skin: May cause skin irritation. Ingestion: May cause irritation of the digestive tract. May be harmful if swallowed. Inhalation: May cause respiratory tract irritation. Chronic: No information found. Section 4 - FIRST AID MEASURES Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately. Skin: Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse. Ingestion: If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately. Inhalation: Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid. Notes to Physician: Treat symptomatically and supportively. Antidote: None reported. Section 5 - FIRE FIGHTING MEASURES General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Extinguishing Media: In case of fire, use water, dry chemical, chemical foam, or alcohol-resistant foam. Section 6 - ACCIDENTAL RELEASE MEASURES General Information: Use proper personal protective equipment as indicated in Section 8. Spills/Leaks: Clean up spills immediately, observing precautions in the Protective Equipment section. Sweep up or absorb material, then place into a suitable clean, dry, closed container for disposal. Avoid generating dusty conditions. Provide ventilation. Section 7 - HANDLING and STORAGE Handling: Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Avoid ingestion and inhalation. Use with adequate ventilation. Storage: Store in a cool, dry, well-ventilated area away from incompatible substances. Keep containers tightly closed. Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION Engineering Controls: Use adequate ventilation to keep airborne concentrations low. Exposure Limits CAS# 154-41-6: Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure. Respirators: Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced. Section 9 - PHYSICAL AND CHEMICAL PROPERTIES Physical State: Powder Color: white Odor: crude benzoic acid pH: Not available. Vapor Pressure: Not available. Viscosity: Not available. Boiling Point: Not available. Freezing/Melting Point: 194.00 - 196.00 deg C Autoignition Temperature: Not applicable. Flash Point: Not applicable. Explosion Limits, lower: Not available. Explosion Limits, upper: Not available. Decomposition Temperature: Solubility in water: Soluble. Specific Gravity/Density: Molecular Formula: C9H13NO.HCl Molecular Weight: 187.67 Section 10 - STABILITY AND REACTIVITY Chemical Stability: Stable under normal temperatures and pressures. Conditions to Avoid: Incompatible materials, light, dust generation, strong oxidants. Incompatibilities with Other Materials: Strong oxidizing agents. Hazardous Decomposition Products: Hydrogen chloride, nitrogen oxides, carbon monoxide, irritating and toxic fumes and gases, carbon dioxide, nitrogen. Hazardous Polymerization: Has not been reported. Section 11 - TOXICOLOGICAL INFORMATION RTECS#: CAS# 154-41-6: DN4200000 LD50/LC50: CAS# 154-41-6: Oral, mouse: LD50 = 150 mg/kg; Oral, rat: LD50 = 1490 mg/kg. Carcinogenicity: DL-Norephedrine hydrochloride - Not listed by ACGIH, IARC, or NTP. Other: See actual entry in RTECS for complete information. Section 12 - ECOLOGICAL INFORMATION Other No information available. Section 13 - DISPOSAL CONSIDERATIONS Dispose of in a manner consistent with federal, state, and local regulations. Section 14 - TRANSPORT INFORMATION IATA Not regulated as a hazardous material. IMO Not regulated as a hazardous material. RID/ADR Not regulated as a hazardous material. Section 15 - REGULATORY INFORMATION European/International Regulations European Labeling in Accordance with EC Directives Hazard Symbols: XN Risk Phrases: R 22 Harmful if swallowed. Safety Phrases: WGK (Water Danger/Protection) CAS# 154-41-6: No information available. Canada CAS# 154-41-6 is listed on Canada's DSL List. CAS# 154-41-6 is not listed on Canada's Ingredient Disclosure List. US FEDERAL TSCA CAS# 154-41-6 is listed on the TSCA inventory. SECTION 16 - ADDITIONAL INFORMATION N/A |
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
|
符号 |
GHS07 |
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信号词 | Warning |
危害声明 | H302 |
警示性声明 | P301 + P312 + P330 |
个人防护装备 | dust mask type N95 (US);Eyeshields;Gloves |
危害码 (欧洲) | Xn: Harmful; |
风险声明 (欧洲) | R22 |
安全声明 (欧洲) | S22-S36/37/39-S45 |
危险品运输编码 | UN 2811 |
WGK德国 | 3 |
RTECS号 | DN4200000 |
海关编码 | 2922199090 |
~82% 154-41-6 |
文献:Oppong-Boachie, Francis Kwabena Bulletin des Societes Chimiques Belges, 1985 , vol. 94, # 4 p. 293 - 298 |
~% 154-41-6 |
文献:Yakugaku Zasshi, , vol. 48, p. 124 Chem. Zentralbl., , vol. 100, # I p. 240 Yakugaku Zasshi, , # 540 p. 18 Chem. Zentralbl., , vol. 98, # I p. 2539 Justus Liebigs Annalen der Chemie, , vol. 470, p. 174 Chem. Zentralbl., , vol. 99, # II p. 2553 |
~% 154-41-6 |
文献:Yakugaku Zasshi, , # 540 p. 18 Chem. Zentralbl., , vol. 98, # I p. 2539 Justus Liebigs Annalen der Chemie, , vol. 470, p. 174 Chem. Zentralbl., , vol. 99, # II p. 2553 |
上游产品 2 | |
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下游产品 6 | |
海关编码 | 2922199090 |
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中文概述 | 2922199090. 其他氨基醇及其醚,酯和它们的盐(但含一种以上含氧基的除外). 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:30.0% |
申报要素 | 品名, 成分含量, 用途, 乙醇胺及其盐应报明色度, 乙醇胺及其盐应报明包装 |
Summary | 2922199090. other amino-alcohols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |