253135-95-4

• 常用中文名：(-)-(3S)-3-氨基-5-苯基-1,3-二氢-2H-1,4-苯并二氮杂卓-2-酮
• 常用英文名：(-)-(3S)-3-Amino-5-phenyl-1,3-dihydro-2H-1,4-benzodiazepin-2-one
• CAS号：253135-95-4
• 分子式：C₁₅H₁₃N₃O
• 分子量：251.28300
• 发布时间：2017-02-05 06:20:22
• 更新时间：2025-08-25 20:51:26

名称

• 中文名: (-)-(3S)-3-氨基-5-苯基-1,3-二氢-2H-1,4-苯并二氮杂卓-2-酮
• 英文名: (3S)-3-amino-5-phenyl-1,3-dihydro-1,4-benzodiazepin-2-one
• 英文别名: 2H-1,4-Benzodiazepin-2-one,3-amino-1,3-dihydro-5-phenyl-,(3S); (S)-3-amino-5-phenyl-1,3-dihydro-benzo[e][1,4]diazepin-2-one; (S)-3-amino-5-phenyl-1,3-dihydro-1H-benzo[e][1,4]diazepin-2-one; (3S)-3-amino-S-phenyl-1,3-dihydro-2H-1,4-benzodiazepin-2-one; (3S)-3-amino-5-phenyl-1,3-dihydro-2H-1,4-benzodiazepin-2-one; (S)-3-amino-1,3-dihydro-5-phenyl-2H-1,4-benzodiazepin-2-one

物化性质

• 分子式: C₁₅H₁₃N₃O
• 分子量: 251.28300
• 精确质量: 251.10600
• PSA: 70.97000
• LogP: 1.98190
• 储存条件: 室温

合成路线

103343-47-1 ~% 253135-95-4

文献：Henderson, Elisa A.; Alber, Dagmar G.; Baxter, Robert C.; Bithell, Sian K.; Budworth, Joanna; Carter, Malcolm C.; Chubb, Ann; Cockerill, G. Stuart; Dowdell, Verity C. L.; Fraser, Ian J.; Harris, Robert A.; Keegan, Sally J.; Kelsey, Richard D.; Lumley, James A.; Stables, Jeremy N.; Weerasekera, Natasha; Wilson, Lara J.; Powell, Kenneth L. Journal of Medicinal Chemistry, 2007 , vol. 50, # 7 p. 1685 - 1692

103343-47-1 ~% 796038-21-6 253135-95-4

文献：Bristol-Myers Squibb Company Patent: US2012/245151 A1, 2012 ; Location in patent: Page/Page column 32-33 ;

676127-93-8 ~% 253135-95-4

文献：Henderson, Elisa A.; Alber, Dagmar G.; Baxter, Robert C.; Bithell, Sian K.; Budworth, Joanna; Carter, Malcolm C.; Chubb, Ann; Cockerill, G. Stuart; Dowdell, Verity C. L.; Fraser, Ian J.; Harris, Robert A.; Keegan, Sally J.; Kelsey, Richard D.; Lumley, James A.; Stables, Jeremy N.; Weerasekera, Natasha; Wilson, Lara J.; Powell, Kenneth L. Journal of Medicinal Chemistry, 2007 , vol. 50, # 7 p. 1685 - 1692

116842-76-3 ~% 253135-95-4

文献：Henderson, Elisa A.; Alber, Dagmar G.; Baxter, Robert C.; Bithell, Sian K.; Budworth, Joanna; Carter, Malcolm C.; Chubb, Ann; Cockerill, G. Stuart; Dowdell, Verity C. L.; Fraser, Ian J.; Harris, Robert A.; Keegan, Sally J.; Kelsey, Richard D.; Lumley, James A.; Stables, Jeremy N.; Weerasekera, Natasha; Wilson, Lara J.; Powell, Kenneth L. Journal of Medicinal Chemistry, 2007 , vol. 50, # 7 p. 1685 - 1692

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