451487-18-6

• 常用中文名：2-[(4-Fluorobenzyl)sulfanyl]-1,5,6,7-tetrahydro-4H-cyclopenta[d]p yrimidin-4-one
• 常用英文名：2-[(4-Fluorobenzyl)sulfanyl]-1,5,6,7-tetrahydro-4H-cyclopenta[d]p yrimidin-4-one
• CAS号：451487-18-6
• 分子式：C₁₄H₁₃FN₂OS
• 分子量：276.329
• 发布时间：2016-01-14 14:20:56
• 更新时间：2024-01-14 17:11:47

名称

• 英文名: 2-[(4-Fluorobenzyl)sulfanyl]-1,5,6,7-tetrahydro-4H-cyclopenta[d]p yrimidin-4-one
• 英文别名: 2-[(4-Fluorobenzyl)sulfanyl]-3,5,6,7-tetrahydro-4H-cyclopenta[d]pyrimidin-4-one; 2-[(4-Fluorobenzyl)sulfanyl]-1,5,6,7-tetrahydro-4H-cyclopenta[d]pyrimidin-4-one; 4H-Cyclopenta[d]pyrimidin-4-one, 2-[[(4-fluorophenyl)methyl]thio]-1,5,6,7-tetrahydro-; Benzene,1-[(4-fluorophenyl)methoxy]-2-iodo-4-(trifluoromethyl); 2-(4-fluorobenzylthio)-6,7-dihydro-1H-cyclopenta[d]-pyrimidin-4(5H)-one; 4H-cyclopenta[d]pyrimidin-4-one, 2-[[(4-fluorophenyl)methyl]thio]-3,5,6,7-tetrahydro-; 2-[(4-fluorobenzyl)oxy]-5-trifluoromethyliodobenzene

物化性质

• 密度: 1.4±0.1 g/cm3
• 沸点: 434.2±47.0 °C at 760 mmHg
• 分子式: C₁₄H₁₃FN₂OS
• 分子量: 276.329
• 闪点: 216.4±29.3 °C
• 精确质量: 276.073273
• PSA: 71.31000
• LogP: 3.14
• 蒸汽压: 0.0±1.0 mmHg at 25°C
• 折射率: 1.677

合成路线

35563-27-0 459-46-1 ~% 451487-18-6

文献：Shanghai Institute of Materia Medica, Chinese Academy of Sciences; SHEN, Jianhua; WANG, Yiping; WANG, Kai Patent: EP2725024 A1, 2014 ; Location in patent: Paragraph 0154 ;

352-11-4 35563-27-0 ~% 451487-18-6

文献：Blackie, Josie A.; Bloomer, Jackie C.; Brown, Murray J. B.; Cheng, Hung-Yuan; Hammond, Beverley; Hickey, Deirdre M. B.; Ife, Robert J.; Leach, Colin A.; Lewis, V. Ann; Macphee, Colin H.; Milliner, Kevin J.; Moores, Kitty E.; Pinto, Ivan L.; Smith, Stephen A.; Stansfield, Ian G.; Stanway, Steven J.; Taylor, Maxine A.; Theobald, Colin J. Bioorganic and Medicinal Chemistry Letters, 2003 , vol. 13, # 6 p. 1067 - 1070

611-10-9 ~% 451487-18-6

文献：Blackie, Josie A.; Bloomer, Jackie C.; Brown, Murray J. B.; Cheng, Hung-Yuan; Hammond, Beverley; Hickey, Deirdre M. B.; Ife, Robert J.; Leach, Colin A.; Lewis, V. Ann; Macphee, Colin H.; Milliner, Kevin J.; Moores, Kitty E.; Pinto, Ivan L.; Smith, Stephen A.; Stansfield, Ian G.; Stanway, Steven J.; Taylor, Maxine A.; Theobald, Colin J. Bioorganic and Medicinal Chemistry Letters, 2003 , vol. 13, # 6 p. 1067 - 1070

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