毒理学数据:
1.试验方法：吸入
摄入剂量： 10 mg/m3/4H
测试对象：啮齿动物-鼠
毒性类型：急性
毒性作用： (1)肺 ，胸部或呼吸-咳嗽
2.试验方法：吸入
摄入剂量： 2 mg/m3/30M/26W-I
测试对象：哺乳动物-物种不详
毒性类型： MutipleDose
毒性作用： (1)心电图变化不影响诊断的指定
(2)肝功能受损
(3)体重减轻或减少体重增加。
3.在潮湿空气中能自燃。加热或接触水或酸类能发生放热反应，也能引起燃烧。能与氧化剂剧烈反应，密集的粉尘遇热或氧化剂接触即行爆炸。粉尘对眼睛、鼻、皮肤和呼吸系统有强刺激作用。遇湿气或水分生成氢氧化锂腐蚀性很强。
4.急性毒性 LD50：77.5mg/kg（大鼠经口）
5.刺激性 家兔经眼：5mg/m3，引起刺激。
生态学数据:
该物质对环境可能有危害，对水体应给予特别注意。
CHEMICAL IDENTIFICATION
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RTECS NUMBER :
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OJ6300000
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CHEMICAL NAME :
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Lithium hydride
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CAS REGISTRY NUMBER :
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7580-67-8
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LAST UPDATED :
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199806
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DATA ITEMS CITED :
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27
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MOLECULAR FORMULA :
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H-Li
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MOLECULAR WEIGHT :
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7.95
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WISWESSER LINE NOTATION :
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LI H
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
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TYPE OF TEST :
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LCLo - Lowest published lethal concentration
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ROUTE OF EXPOSURE :
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Inhalation
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SPECIES OBSERVED :
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Rodent - rat
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DOSE/DURATION :
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10 mg/m3/4H
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TOXIC EFFECTS :
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Lungs, Thorax, or Respiration - cough
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REFERENCE :
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AMIHAB AMA Archives of Industrial Health. (Chicago, IL) V.11-21, 1955-60. For publisher information, see AEHLAU. Volume(issue)/page/year: 14,468,1956 ** OTHER MULTIPLE DOSE TOXICITY DATA **
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TYPE OF TEST :
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TCLo - Lowest published toxic concentration
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ROUTE OF EXPOSURE :
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Inhalation
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SPECIES OBSERVED :
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Rodent - rat
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DOSE/DURATION :
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5 mg/m3/4H/1W-I
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TOXIC EFFECTS :
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Sense Organs and Special Senses (Olfaction) - effect, not otherwise specified Skin and Appendages - dermatitis, other (after systemic exposure)
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REFERENCE :
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AMIHAB AMA Archives of Industrial Health. (Chicago, IL) V.11-21, 1955-60. For publisher information, see AEHLAU. Volume(issue)/page/year: 14,468,1956
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TYPE OF TEST :
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TCLo - Lowest published toxic concentration
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ROUTE OF EXPOSURE :
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Inhalation
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SPECIES OBSERVED :
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Rodent - mouse
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DOSE/DURATION :
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5 mg/m3/4H/1W-I
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TOXIC EFFECTS :
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Sense Organs and Special Senses (Olfaction) - effect, not otherwise specified Skin and Appendages - dermatitis, other (after systemic exposure)
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REFERENCE :
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AMIHAB AMA Archives of Industrial Health. (Chicago, IL) V.11-21, 1955-60. For publisher information, see AEHLAU. Volume(issue)/page/year: 14,468,1956
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TYPE OF TEST :
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TCLo - Lowest published toxic concentration
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ROUTE OF EXPOSURE :
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Inhalation
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SPECIES OBSERVED :
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Rodent - rabbit
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DOSE/DURATION :
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5 mg/m3/4H/1W-I
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TOXIC EFFECTS :
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Sense Organs and Special Senses (Olfaction) - effect, not otherwise specified Sense Organs and Special Senses (Eye) - effect, not otherwise specified Skin and Appendages - dermatitis, other (after systemic exposure)
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REFERENCE :
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AMIHAB AMA Archives of Industrial Health. (Chicago, IL) V.11-21, 1955-60. For publisher information, see AEHLAU. Volume(issue)/page/year: 14,468,1956
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TYPE OF TEST :
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TCLo - Lowest published toxic concentration
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ROUTE OF EXPOSURE :
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Inhalation
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SPECIES OBSERVED :
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Rodent - guinea pig
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DOSE/DURATION :
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5 mg/m3/4H-I
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REFERENCE :
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AMIHAB AMA Archives of Industrial Health. (Chicago, IL) V.11-21, 1955-60. For publisher information, see AEHLAU. Volume(issue)/page/year: 14,468,1956 *** REVIEWS *** ACGIH TLV-TWA 0.025 mg/m3 DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: TLV/BEI,1997 *** U.S. STANDARDS AND REGULATIONS *** MSHA STANDARD-air:TWA 0.025 mg/m3 DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: 3,147,1971 OSHA PEL (Gen Indu):8H TWA 0.025 mg/m3 CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1910.1000,1994 OSHA PEL (Construc):8H TWA 0.025 mg/m3 CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1926.55,1994 OSHA PEL (Shipyard):8H TWA 0.025 mg/m3 CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1915.1000,1993 OSHA PEL (Fed Cont):8H TWA 0.025 mg/m3 CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 41,50-204.50,1994 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-AUSTRALIA:TWA 0.025 mg/m3 JAN 1993 OEL-BELGIUM:TWA 0.025 mg/m3 JAN 1993 OEL-DENMARK:TWA 0.025 mg/m3 JAN 1993 OEL-FINLAND:TWA 0.025 mg/m3;STEL 0.075 mg/m3 JAN 1993 OEL-FRANCE:TWA 0.025 mg/m3 JAN 1993 OEL-GERMANY:TWA 0.025 mg/m3 JAN 1993 OEL-THE NETHERLANDS:TWA 0.025 mg/m3 JAN 1993 OEL-THE PHILIPPINES:TWA 0.025 mg/m3 JAN 1993 OEL-SWITZERLAND:TWA 0.025 mg/m3 JAN 1993 OEL-TURKEY:TWA 0.025 mg/m3 JAN 1993 OEL-UNITED KINGDOM:TWA 0.025 mg/m3 JAN 1993 OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV OEL IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGIH TLV *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH RECOMMENDED EXPOSURE LEVEL (REL) : NIOSH REL TO LITHIUM HYDRIDE-air:10H TWA 0.025 mg/m3 REFERENCE : NIOSH* National Institute for Occupational Safety and Health, U.S. Dept. of Health, Education, and Welfare, Reports and Memoranda. Volume(issue)/page/year: DHHS #92-100,1992 NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 43115 No. of Facilities: 11 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 11 (estimated)
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