372-37-2

• 常用中文名：4-氟乙酰乙酸乙酯
• 常用英文名：Butanoic acid,4-fluoro-3-oxo-, ethyl ester
• CAS号：372-37-2
• 分子式：C₆H₉FO₃
• 分子量：148.13200
• 发布时间：2016-01-14 08:02:51
• 更新时间：2024-01-16 09:25:52

名称

• 中文名: 4-氟乙酰乙酸乙酯
• 英文名: ethyl 4-fluoro-3-oxobutanoate
• 英文别名: 4-fluoro-acetoacetic acid ethyl ester; 4-fluoro-3-oxo-butyric acid ethyl ester; ethyl 2-fluoro-acetoacetate; ACETOACETIC ACID,4-FLUORO-,ETHYL ESTER; ethyl 4-fluoro-3-oxo-butanoate; WLN: F1V1VO2; 4-Fluor-acetessigsaeure-aethylester; Ethyl 4-fluoroacetoacetate

物化性质

• 密度: 1.108g/cm3
• 沸点: 178.5ºC at 760mmHg
• 分子式: C₆H₉FO₃
• 分子量: 148.13200
• 闪点: 60.5ºC
• 精确质量: 148.05400
• PSA: 43.37000
• LogP: 0.47820

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : AK5500000 CHEMICAL NAME : Acetoacetic acid, 4-fluoro-, ethyl ester CAS REGISTRY NUMBER : 372-37-2 BEILSTEIN REFERENCE NO. : 1761273 LAST UPDATED : 199612 DATA ITEMS CITED : 1 MOLECULAR FORMULA : C6-H9-F-O3 MOLECULAR WEIGHT : 148.15 WISWESSER LINE NOTATION : F1V1VO2 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 2500 ug/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : JACSAT Journal of the American Chemical Society. (American Chemical Soc., Distribution Office Dept. 223, POB 57136, West End Stn., Washington, DC 20037) V.1- 1879- Volume(issue)/page/year: 79,1959,1957

安全

• 海关编码: 2918300090

合成路线

459-72-3 141-78-6 ~% 372-37-2

文献：SCHERING CORPORATION; SOUTHERN RESEARCH INSTITUTE; ARASAPPAN, Ashok; NJOROGE, F., George; BENNETT, Frank; GIRIJAVALLABHAN, Vinay, M.; HUANG, Yuhua; HUELGAS, Regina; PIWINSKI, John, J.; SHIH, Neng-Yang; VERMA, Vishal; VELAZQUEZ, Francisco; VENKATRAMAN, Srikanth; KWONG, Cecil, D.; ANANTHAN, Subramaniam; CLARK, Jeremy; GENG, Feng; KEZAR, Hollis, S., III.; MADDRY, Joseph, A.; REYNOLDS, Robert, C.; ROYCHOWDHURY, Abhijit; SECRIST, John, A., III.; FOWLER, Anita, T. Patent: WO2010/22121 A1, 2010 ; Location in patent: Page/Page column 176 ;

459-72-3 105-39-5 ~% 372-37-2

文献：Loos; Herman Bulletin des Societes Chimiques Belges, 1959 , vol. 68, p. 129,132 Full Text Show Details Bergmann et al. Journal of the Chemical Society, 1959 , p. 3278,3282

459-72-3 105-36-2 ~% 372-37-2

文献：Loos; Herman Bulletin des Societes Chimiques Belges, 1959 , vol. 68, p. 129,132 Full Text Show Details Bergmann et al. Journal of the Chemical Society, 1959 , p. 3278,3282

上下游产品

上游产品  4
459-72-3 141-78-6 105-39-5 105-36-2
下游产品  4
787-07-5 1598-64-7 1598-62-5 3110-42-7

海关

海关编码	2918300090
中文概述	2918300090 其他含醛基或酮基不含其他含氧基羧酸（包括酸酐、酰卤化物、过氧化物和过氧酸及该税号的衍生物）. 增值税率:17.0% 退税率:9.0% 监管条件:无 最惠国关税:6.5% 普通关税:30.0%
申报要素	品名, 成分含量, 用途
Summary	2918300090 other carboxylic acids with aldehyde or ketone function but without other oxygen function, their anhydrides, halides, peroxides, peroxyacids and their derivatives。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%