21820-82-6

• 常用中文名：Fenpipalone
• 常用英文名：Fenpipalone
• CAS号：21820-82-6
• 分子式：C₁₇H₂₂N₂O₂
• 分子量：286.36900
• 发布时间：2017-11-16 06:40:20
• 更新时间：2025-08-25 19:28:56

名称

• 英文名: 3-methyl-5-[2-(4-phenyl-3,6-dihydro-2H-pyridin-1-yl)ethyl]-1,3-oxazolidin-2-one
• 英文别名: Fenpipalona; 2-Oxazolidinone,5-(2-(3,6-dihydro-4-phenyl-1(2H)-pyridyl)ethyl)-3-methyl; FENPIPALONE; 2-Oxazolidinone,5-(2-(3,6-dihydro-4-phenyl-1(2H)-pyridinyl)ethyl)-3-methyl; AHR-1680; 3-methyl-5-[2-(4-phenyl-3,6-dihydro-2H-pyridin-1-yl)-ethyl]-oxazolidin-2-one; Fenpipalonum [INN-Latin]; 5-(2-(3,6-Dihydro-4-phenyl-1(2H)-pyridyl)ethyl)-3-methyl-2-oxazolidinone; Fenpipalona [INN-Spanish]

物化性质

• 密度: 1.127g/cm3
• 沸点: 486.9ºC at 760mmHg
• 分子式: C₁₇H₂₂N₂O₂
• 分子量: 286.36900
• 闪点: 248.3ºC
• 精确质量: 286.16800
• PSA: 32.78000
• LogP: 2.49220
• 蒸汽压: 1.24E-09mmHg at 25°C
• 折射率: 1.557

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : RQ2625000 CHEMICAL NAME : 2-Oxazolidinone, 5-(2-(3,6-dihydro-4-phenyl-1(2H)-pyridyl)ethyl)-3-met hyl- CAS REGISTRY NUMBER : 21820-82-6 LAST UPDATED : 199612 DATA ITEMS CITED : 8 MOLECULAR FORMULA : C17-H22-N2-O2 MOLECULAR WEIGHT : 286.41 WISWESSER LINE NOTATION : T6N CUTJ DR& A2- DT5NVOTJ A1 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 340 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : 27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,200,1972 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 140 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : 27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,200,1972 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 71 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : 27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,200,1972 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 349 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : 27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,200,1972 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 180 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : 27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,200,1972 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 91 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : 27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,200,1972 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Mammal - dog DOSE/DURATION : 300 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : 27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,200,1972 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - guinea pig DOSE/DURATION : 189 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : 27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,200,1972

合成路线

43064-12-6 13999-24-1 ~% 21820-82-6

文献：Welstead Jr.; Helsley; Taylor; Turnbull; DaVanzo; Funderburk; Alphin Journal of Medicinal Chemistry, 1973 , vol. 16, # 10 p. 1129 - 1132

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