5-(2-Aminoethyl)-2-oxazolidinones with central nervous system depressant and antiinflammatory activity

WJ Welstead Jr, GC Helsley, CR Taylor…

文献索引：Welstead Jr.; Helsley; Taylor; Turnbull; DaVanzo; Funderburk; Alphin Journal of Medicinal Chemistry, 1973 , vol. 16, # 10 p. 1129 - 1132

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被引用次数: 3

摘要

The reaction of chloroethyloxazolidinones with amines as described in the preceding paper has led to compounds with interesting pharmacological activity. l In our continuing effort to uncover compounds with useful CNS depressant activity, we have extended this original exploratory work to include a series of aminoethyloxazolidinones prepared from aryl- substituted piperidines, pyrrolidines, and related cyclic amines. Several of the compounds ...