CHEMICAL IDENTIFICATION
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RTECS NUMBER :
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LX9150000
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CHEMICAL NAME :
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Gelsemine, monohydrochloride
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CAS REGISTRY NUMBER :
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35306-33-3
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LAST UPDATED :
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199203
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DATA ITEMS CITED :
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2
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MOLECULAR FORMULA :
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C20-H22-N2-O2.Cl-H
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
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TYPE OF TEST :
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LD50 - Lethal dose, 50 percent kill
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ROUTE OF EXPOSURE :
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Intravenous
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SPECIES OBSERVED :
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Rodent - mouse
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DOSE/DURATION :
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4 mg/kg
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TOXIC EFFECTS :
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Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - other changes Gastrointestinal - changes in structure or function of salivary glands
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REFERENCE :
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DUSA** "Dispensatory of the United States of America," 24th ed., Osol, A. and G.E. Farrar, Philadelphia, J.B. Lippincott Co., 1947 Volume(issue)/page/year: 24,497,1947
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TYPE OF TEST :
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LDLo - Lowest published lethal dose
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ROUTE OF EXPOSURE :
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Subcutaneous
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SPECIES OBSERVED :
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Rodent - rabbit
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DOSE/DURATION :
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500 ug/kg
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TOXIC EFFECTS :
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Lungs, Thorax, or Respiration - other changes Liver - other changes Kidney, Ureter, Bladder - other changes
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REFERENCE :
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ZEBLA3 Zeitschrift fuer Biologie. (Munich, Fed. Rep. Ger.) V.1-116, 1865-1971. Discontinued. Volume(issue)/page/year: 99,446,1939
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