64204-55-3

• 常用中文名：艾沙拉唑
• 常用英文名：N-Cyclohexyl-2-piperazin-1-yl-acetamide
• CAS号：64204-55-3
• 分子式：C₁₂H₂₃N₃O
• 分子量：225.33100
• 发布时间：2018-05-31 08:00:00
• 更新时间：2025-09-16 09:45:12

名称

• 中文名: 艾沙拉唑
• 英文名: N-cyclohexyl-2-piperazin-1-ylacetamide
• 中文别名: N-环己基-2-哌嗪-1-基乙酰胺双盐酸盐
• 英文别名: Hexaprazol; N-cyclohexyl-piperazino-acetamide; Exaprazole; N-Cyclohexyl-1-piperazineacetamide; hexaprazole; Esaprazole; N-Cyclohexyl-2-piperazin-1-yl-acetamide; N-cyclohexyl-1-piperazino acetamide

物化性质

• 密度: 1.07g/cm3
• 沸点: 419ºC at 760 mmHg
• 分子式: C₁₂H₂₃N₃O
• 分子量: 225.33100
• 闪点: 207.2ºC
• 精确质量: 225.18400
• PSA: 44.37000
• LogP: 0.99810
• 折射率: 1.532

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : TK7801300 CHEMICAL NAME : 1-Piperazineacetamide, N-cyclohexyl- CAS REGISTRY NUMBER : 64204-55-3 BEILSTEIN REFERENCE NO. : 0785765 LAST UPDATED : 199612 DATA ITEMS CITED : 3 MOLECULAR FORMULA : C12-H23-N3-O MOLECULAR WEIGHT : 225.38 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 3900 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : USXXAM United States Patent Document. (U.S. Patent Office, Box 9, Washington, DC 20231) Volume(issue)/page/year: #4123530 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 1974 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : USXXAM United States Patent Document. (U.S. Patent Office, Box 9, Washington, DC 20231) Volume(issue)/page/year: #4123530 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 271 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : USXXAM United States Patent Document. (U.S. Patent Office, Box 9, Washington, DC 20231) Volume(issue)/page/year: #4123530

安全

• 危害码 (欧洲): Xi
• 海关编码: 2933599090

合成路线

110-85-0 23605-23-4 ~79% 64204-55-3

文献：Hulinska, Hana; Polivka, Zdenek; Jilek, Jiri; Sindelar, Karel; Holubek, Jiri; et al. Collection of Czechoslovak Chemical Communications, 1988 , vol. 53, # 8 p. 1820 - 1844

108-91-8 ~% 64204-55-3

文献：Barn, David R.; Morphy, J. Richard; Rees, David C. Tetrahedron Letters, 1996 , vol. 37, # 18 p. 3213 - 3216

上下游产品

上游产品  3
110-85-0 23605-23-4 108-91-8
下游产品  0

海关

海关编码	2933599090
中文概述	2933599090. 其他结构上有嘧啶环的化合物(包括其他结构上有哌嗪环的化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
Summary	2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%