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92339-11-2价格

92339-11-2

92339-11-2结构式
92339-11-2结构式
  • 常用中文名:碘克沙醇
  • 常用英文名:Iodixanol
  • CAS号:92339-11-2
  • 分子式:C35H44I6N6O15
  • 分子量:1550.182
  • 相关类别: 原料药 诊断用药 影象检查用药
  • 发布时间:2018-03-29 08:00:00
  • 更新时间:2024-01-04 13:51:52
  • Iodixanol 是一种含碘的非离子放射性造影剂。

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中文名 碘克沙醇
英文名 iodixanol
中文别名 5,5'-((2-羟基-1,3-丙烷)双(乙酰亚氨))双(N,N'-二(2,3-二羟基丙基)-2,4,6-三碘-1,3-苯二甲酰胺
碘海醇
1,3-双(乙酰胺基)-N,N'-双[3,5-双(2,3-二羟丙基氨羰基)-2,4,6-三碘苯基]-2-羟基丙烷
英文别名 1,3-Benzenedicarboxamide, 5,5'-[(2-hydroxy-1,3-propanediyl)bis(acetylimino)]bis[N,N'-bis(2,3-dihydroxypropyl)-2,4,6-triiodo-
5,5'-[(2-Hydroxypropane-1,3-diyl)bis(acetylimino)]bis[N,N'-bis(2,3-dihydroxypropyl)-2,4,6-triiodoisophthalamide]
Q1YQ1MVR BI DI FI CVM1YQ1Q ENV1&1YQ1NV1&R BI DI FI CVM1YQ1Q EVM1YQ1Q
1,3-bis(acetylamino)-N,N'-bis[3,5-bis(2,3-dihydroxypropylaminocarbonyl)-2,4,6-triiodophenyl]-2-hydroxypropane
Iodixanolum [Latin]
Visipaque
Indixanol
3,3',5,5'-tetrakis(2,3-dihydroxypropylcarbamoyl)-2,2',4,4',6,6'-hexaiodo-N,N'-(2-hydroxypropane-1,3-diyl)diacetanilide
visipaqueTM
1,3-Benzenedicarboxamide, 5,5'-[(2-hydroxy-1,3-propanediyl)bis(acetylimino)]bis[N,N-bis(2,3-dihydroxypropyl)-2,4,6-triiodo-
5-[acetyl-[3-[N-acetyl-3,5-bis(2,3-dihydroxypropylcarbamoyl)-2,4,6-triiodoanilino]-2-hydroxypropyl]amino]-1-N,3-N-bis(2,3-dihydroxypropyl)-2,4,6-triiodobenzene-1,3-dicarboxamide
Iodixanolum
Visipaque 270
3,3',5',5'-tetrakis(2,3-dixydroxypropylcarbamoyl)-2,2',4,4',6,6'-hexaiodo-N,N'-(2-hydroxypropane-1,3-diyl)diacetanilide
UNII-HW8W27HTXX
5,5'-[(2-Hydroxy-1,3-propanediyl)bis(acetylimino)]bis[N,N'-bis(2,3-dihydroxypropyl)-2,4,6-triiodoisophthalamide]
Iodixanol
Visipaque 320
描述 Iodixanol 是一种含碘的非离子放射性造影剂。
相关类别
体内研究 碘xanol表现出较少的肾毒性[1]。
参考文献

[1]. Iodixanol.

密度 2.3±0.1 g/cm3
沸点 1250.9±65.0 °C at 760 mmHg
熔点 262-267ºC (dec.)
分子式 C35H44I6N6O15
分子量 1550.182
闪点 710.3±34.3 °C
精确质量 1549.713257
PSA 339.09000
LogP -5.88
外观性状 灰白色至白色粉末
蒸汽压 0.0±0.3 mmHg at 25°C
折射率 1.752
储存条件 Refrigerator
水溶解性 Freely soluble in water, sparingly soluble in methanol, practically insoluble in methylene chloride.

CHEMICAL IDENTIFICATION

RTECS NUMBER :
CZ3075000
CHEMICAL NAME :
1,3-Benzenedicarboxamide, 5,5'-((2-hydroxy-1,3-propanediyl)bis(acetylimino))bis (N,N'- bis(2,3-dihydroxypropyl)-2,4,6-triiodo-
CAS REGISTRY NUMBER :
92339-11-2
LAST UPDATED :
199806
DATA ITEMS CITED :
4

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>42757 mg/kg
TOXIC EFFECTS :
Lungs, Thorax, or Respiration - acute pulmonary edema Kidney, Ureter, Bladder - changes in tubules (including acute renal failure, acute tubular necrosis) Blood - hemorrhage
REFERENCE :
ARASA5 Acta Radiologica, Supplementum. (Acta Radiologica, POB 7449, S-10391 Stockholm, Sweden) No.1- 1921- Volume(issue)/page/year: 399,69,1995
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
30512 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity) Lungs, Thorax, or Respiration - dyspnea Kidney, Ureter, Bladder - changes in tubules (including acute renal failure, acute tubular necrosis)
REFERENCE :
ARASA5 Acta Radiologica, Supplementum. (Acta Radiologica, POB 7449, S-10391 Stockholm, Sweden) No.1- 1921- Volume(issue)/page/year: 399,69,1995 ** OTHER MULTIPLE DOSE TOXICITY DATA **
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
73228 mg/kg/3W-I
TOXIC EFFECTS :
Kidney, Ureter, Bladder - changes in tubules (including acute renal failure, acute tubular necrosis) Kidney, Ureter, Bladder - urine volume increased Kidney, Ureter, Bladder - other changes in urine composition
REFERENCE :
ARASA5 Acta Radiologica, Supplementum. (Acta Radiologica, POB 7449, S-10391 Stockholm, Sweden) No.1- 1921- Volume(issue)/page/year: 399,69,1995
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Primate - monkey
DOSE/DURATION :
54921 mg/kg/3W-I
TOXIC EFFECTS :
Kidney, Ureter, Bladder - changes in tubules (including acute renal failure, acute tubular necrosis)
REFERENCE :
ARASA5 Acta Radiologica, Supplementum. (Acta Radiologica, POB 7449, S-10391 Stockholm, Sweden) No.1- 1921- Volume(issue)/page/year: 399,69,1995

危险品运输编码 NONH for all modes of transport
海关编码 2924299090

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文献:US7696381 B1, ; Page/Page column 4 ;

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文献:HOVIONE CHINA HOLDING LIMITED; HU, Zhiqi; ZHANG, Huoying Patent: WO2011/63551 A1, 2011 ; Location in patent: Page/Page column 18 ;

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文献:WO2011/63551 A1, ; Page/Page column 15-16 ;

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文献:US7696381 B1, ; Page/Page column 4 ;

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文献:US2011/21829 A1, ; Page/Page column 5 ;
上游产品  4

下游产品  0

【方法1】
化合物(Ⅰ)和1,3-二氯-2-丙醇缩合,即得碘克沙醇。
海关编码 2924299090
中文概述 2924299090. 其他环酰胺(包括环氨基甲酸酯)(包括其衍生物以及他们的盐). 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:30.0%
申报要素 品名, 成分含量, 用途, 包装
Summary 2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%