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肾上腺酮

肾上腺酮用途

Adrenalone is an adrenergic agonist used as a topical vasoconstrictor and hemostatic.

肾上腺酮名称

[ CAS 号 ]:
99-45-6

[ 中文名 ]:
肾上腺酮

[ 英文名 ]:
ADRENALONE

[中文别名 ]:

3',4'-二羟基-2-(甲基氨基)苯乙酮

[英文别名 ]:

Stypnon
Ethanone, 1-(3,4-dihydroxyphenyl)-2-(methylamino)-
1-(3,4-dihydroxy-phenyl)-2-methylamino-ethanone
EINECS 202-756-9
1-(3,4-Dihydroxyphenyl)-2-(methylamino)ethanone
Adrenone
Stryphnonasal
4-Methylaminocetopyrocatechol
ADRENALONE
Adrenolone

肾上腺酮物理化学性质

[ 密度 ]:
1.3±0.1 g/cm3

[ 沸点 ]:
405.6±40.0 °C at 760 mmHg

[ 熔点 ]:
235.5°C (rough estimate)

[ 分子式 ]:
C₉H₁₁NO₃

[ 分子量 ]:
181.189

[ 闪点 ]:
199.1±27.3 °C

[ 精确质量 ]:
181.073898

[ PSA ]:
69.56000

[ LogP ]:
0.67

[ 外观性状 ]:
浅黄色至明黄色固体

[ 蒸汽压 ]:
0.0±1.0 mmHg at 25°C

[ 折射率 ]:
1.589

[ 储存条件 ]:
20°C，惰性气体

肾上腺酮毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: AM8050000

CHEMICAL NAME :: Acetophenone, 3',4'-dihydroxy-2-(methylamino)-

CAS REGISTRY NUMBER :: 99-45-6

BEILSTEIN REFERENCE NO. :: 2366101

LAST UPDATED :: 199612

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C9-H11-N-O3

MOLECULAR WEIGHT :: 181.21

WISWESSER LINE NOTATION :: QR BQ DV1M1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 275 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Unreported

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 2 gm/kg

TOXIC EFFECTS :: Autonomic Nervous System - sympathomimetic

MUTATION DATA

TYPE OF TEST :: DNA damage

TEST SYSTEM :: Rodent - rat Lung

DOSE/DURATION :: 250 umol/L

REFERENCE :: ABCHA6 Agricultural and Biological Chemistry. (Maruzen Co. Ltd., POB 5050, Tokyo International, Tokyo 100-31, Japan) V.25- 1961- Volume(issue)/page/year: 42,1019,1978

肾上腺酮安全信息

[ 海关编码 ]:
2922509090

肾上腺酮合成路线

详细合成路线

肾上腺酮上下游产品

肾上腺酮上游产品

肾上腺酮下游产品

肾上腺酮制备

由儿茶酚、氯乙酸、三氯氧磷经弗-克反应生成氯乙酰儿茶酚，再用甲胺进行胺化反应得到肾上腺酮。

肾上腺酮海关

[ 海关编码 ]: 2922509090

[ 中文概述 ]:
2922509090. 其他氨基醇酚、氨基酸酚及其他含氧基氨基化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件：AB. 最惠国关税:6.5%. 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 乙醇胺及其盐应报明色度, 乙醇胺及其盐应报明包装

[ 监管条件 ]: A.入境货物通关单 B.出境货物通关单

[ 检验检疫 ]: R.进口食品卫生监督检验 S.出口食品卫生监督检验

[ Summary ]:
2922509090. other amino-alcohol-phenols, amino-acid-phenols and other amino-compounds with oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%