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对氯苯磺酰氯

对氯苯磺酰氯用途

该产品主要用于医药、工程塑料、农药中间体及有机合成原料对氯苯磺酰胺的制备。用于生产农药杀螨剂螨卵酯、医药泰尔登等。对氯苯磺酰氯是除草剂氨磺乐灵的中间体，也是杀螨剂螨卵酯、医药泰尔登的中间体

对氯苯磺酰氯名称

[ CAS 号 ]:
98-60-2

[ 中文名 ]:
4-氯苯磺酰氯

[ 英文名 ]:
4-Chlorobenzenesulfonyl chloride

[中文别名 ]:

[英文别名 ]:

4-chloro-benzenesulfonylchlorid
4-CHLOROBENZENE-1-SULPHONYL CHLORIDE
4-CHLOROBENZENESULFONYL
4-CHLORO-BENZENESULFONYL CHLORIDE
CHLOROBENZENESULFONYL CHLORIDE
4-CHLOROBENZENE SULFONYL CHLORIDE
4-Chlorobenzenesulfonyl chloride
4-CHOROBENZENESULPHONYL CHLORIDE
MFCD00007439
4-Chlorobenzenesulfo

对氯苯磺酰氯物理化学性质

[ 密度 ]:
1.5±0.1 g/cm3

[ 沸点 ]:
272.8±13.0 °C at 760 mmHg

[ 熔点 ]:
50-52 °C(lit.)

[ 分子式 ]:
C₆H₄Cl₂O₂S

[ 分子量 ]:
211.066

[ 闪点 ]:
118.8±19.8 °C

[ 精确质量 ]:
209.930908

[ PSA ]:
42.52000

[ LogP ]:
2.84

[ 外观性状 ]:
白色棱状晶体。溶于乙醇，不溶于水。

[ 蒸汽压 ]:
0.0±0.5 mmHg at 25°C

[ 折射率 ]:
1.569

[ 储存条件 ]:
存放于惰性气体之中;避免湿气 (分解)

[ 水溶解性 ]:
INSOLUBLE

对氯苯磺酰氯MSDS

对氯苯磺酰氯毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: DB8925000

CHEMICAL NAME :: Benzenesulfonyl chloride, p-chloro-

CAS REGISTRY NUMBER :: 98-60-2

BEILSTEIN REFERENCE NO. :: 0511583

LAST UPDATED :: 199709

DATA ITEMS CITED :: 5

MOLECULAR FORMULA :: C6-H4-Cl2-O2-S

MOLECULAR WEIGHT :: 211.06

WISWESSER LINE NOTATION :: WSGR DG

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

REFERENCE :: 85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,1071,1986

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration into the eye

SPECIES OBSERVED :: Rodent - rabbit

REFERENCE :: 85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,1071,1986 ** ACUTE TOXICITY DATA **

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 4250 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,1071,1986

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 250 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: CBCCT* "Summary Tables of Biological Tests," National Research Council Chemical-Biological Coordination Center. (National Academy of Science Library, 2101 Constitution Ave., NW, Washington, DC 20418) Volume(issue)/page/year: 7,774,1955

对氯苯磺酰氯安全信息

[ 符号 ]:

GHS05

[ 信号词 ]:
Danger

[ 危害声明 ]:
H314

[ 警示性声明 ]:
P280-P305 + P351 + P338-P310

[ 个人防护装备 ]:
Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges

[ 危害码 (欧洲) ]:
C

[ 风险声明 (欧洲) ]:
R34:Causes burns. R37:Irritating to the respiratory system.

[ 安全声明 (欧洲) ]:
S26-S28-S36/37/39-S45

[ 危险品运输编码 ]:
UN 3261 8/PG 2

[ WGK德国 ]:
2

[ RTECS号 ]:
DB8925000

[ 包装等级 ]:
II

[ 危险类别 ]:
8

[ 海关编码 ]:
29049020

对氯苯磺酰氯合成路线

对氯苯磺酰氯上下游产品

对氯苯磺酰氯上游产品

对氯苯磺酰氯下游产品

对氯苯磺酰氯制备

1、对氨基苯磺酸法采用对氨基苯磺酸为原料，经重氮化、Sandmeyer反应生成对氯苯磺酸，加入氢氧化钠生成对氯苯磺酸钠，将其加入氯磺酸中，在40-60℃反应3.5h，冷后滴入冰水中，150℃下过滤，洗涤至ph＝5.5-6即得到产品，经过重结晶提纯得到高纯度产品。由于对氨基苯磺酸法反应路线长、成本高，目前我国已经没有生产单位采用。

2、氯苯和氯磺酸法采用氯苯和氯磺酸为原料，将氯磺酸和硫酸冷却至20℃以下，在强烈搅拌下加入氯苯，于23-25℃反应2-3h，升温至60℃，保持2h，冷却过滤即得到产品，经过重结晶提纯得到高纯度产品。原料消耗定额：氯磺酸2200kg/t、氯苯650kg/t、硫酸350kg/t。

3、其制备方法是由氯苯氯磺化制得。将氯磺酸与发烟硫酸混合后冷至20℃以下，在强烈搅拌下加入氯苯，于23～25℃反应2～3 h，再升温60℃反应2 h，冷却、滤干、洗去酸性而得。此外，也可用对氯苯磺酸在60℃与氯磺酸反应1.5 h而得。

对氯苯磺酰氯海关

[ 海关编码 ]: 2904909090

[ 中文概述 ]:
2904909090 其他烃的磺化、硝化、亚硝化衍生物（不论是否卤化）. 增值税率:17.0% 退税率:9.0% 监管条件:无最惠国关税:5.5% 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ Summary ]:
HS:2904909090 sulphonated, nitrated or nitrosated derivatives of hydrocarbons, whether or not halogenated VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%

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