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异蒲勒醇

异蒲勒醇用途

(-)-异戊二醇是在固体负载酸催化和无溶剂微波辅助烯环化作用下直接从香茅精油处理中制备的。(-)-异戊二醇在与羰基化合物反应中表现出高活性。(-)-异戊二醇可用于抗病毒活性研究[1]。

异蒲勒醇名称

[ CAS 号 ]:
89-79-2

[ 中文名 ]:
异蒲勒醇

[ 英文名 ]:
ISOPULEGOL

[中文别名 ]:

(-)-异蒲勒醇

[英文别名 ]:

(-)-Isopulegol
ISOPULEGOL (P-MENTH-8-EN-3-OL)
ISO-PULEGOL
ISOPULEGOL
EINECS 201-940-6
MFCD00134655
FEMA 2962
P-MENTH-8-EN-3-OL

异蒲勒醇生物活性

[ 描述 ]:

[ 相关类别 ]:

研究领域 >> 感染

信号通路 >> 其他 >> 其他

[参考文献]

[1]. Raquel G.Jacob, et al. Green synthesis of (−)-isopulegol from (+)-citronellal: application to essential oil of citronella. Tetrahedron Letters. 2003 April 28;44(18):3605-3608.

[2]. Ilyina IV, et al. Highly potent activity of isopulegol-derived substituted octahydro-2H-chromen-4-ols against influenza A and B viruses. Bioorg Med Chem Lett. 2018 Jun 15;28(11):2061-2067.

异蒲勒醇物理化学性质

[ 密度 ]:
0.912 g/mL at 25 °C(lit.)

[ 沸点 ]:
212 °C(lit.)

[ 分子式 ]:
C₁₀H₁₈O

[ 分子量 ]:
154.24900

[ 闪点 ]:
195 °F

[ 精确质量 ]:
154.13600

[ PSA ]:
20.23000

[ LogP ]:
2.35960

[ 折射率 ]:
n20/D 1.471(lit.)

[ 储存条件 ]:
?20°C

异蒲勒醇MSDS

详细MSDS(安全技术说明书)

异蒲勒醇安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H302-H315-H319-H335

[ 警示性声明 ]:
P261-P305 + P351 + P338

[ 个人防护装备 ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ 危害码 (欧洲) ]:
Xn: Harmful;

[ 风险声明 (欧洲) ]:
R21/22

[ 安全声明 (欧洲) ]:
S26-S36/37/39

[ 危险品运输编码 ]:
NA 1993 / PGIII

[ WGK德国 ]:
2

[ 海关编码 ]:
2906199090

异蒲勒醇海关

[ 海关编码 ]: 2906199090

[ 中文概述 ]:
2906199090. 其他环烷醇，环烯醇及环萜烯醇. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:5.5%. 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ Summary ]:
2906199090. cyclanic, cyclenic or cyclotherpenic alcohols. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:5.5%. General tariff:30.0%

异蒲勒醇文献

Modifications of the chemical structure of terpenes in antiplasmodial and antifungal drug research.

Bioorg. Med. Chem. Lett. 17 , 6075-8, (2007)

Pure natural monoterpenes were evaluated in vitro for their antiplasmodial activities against Plasmodium falciparum. Chemically modified terpenes were also tested to see whether the introduction of an...

[The metabolic products of microorganisms. Boromycin].

Helv. Chim. Acta 50 , 153, (1967)

G. Schmid, W. Hofheinz

J. Am. Chem. Soc. 105 , 624, (1983)

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