9-乙基鸟嘌呤

9-乙基鸟嘌呤用途

9-Ethylguanine is a model nucleobase that is used to study DNA interactions with organometallic complexes, especially those designed to target tumors.

9-乙基鸟嘌呤名称

[ CAS 号 ]:
879-08-3

[ 中文名 ]:
9-乙基鸟嘌呤

[ 英文名 ]:
9-ethylguanine

[英文别名 ]:

2-amino-9-ethyl-9h-purin-6-ol
2-ethylguanine
9-EtG
Guanine,9-ethyl
9-ethylguanosine
6-Amino-9-ethyl-2-hydroxypurine
9-Ethylquanine
N7-ethylguanine
9-Ethylguanine

9-乙基鸟嘌呤物理化学性质

[ 密度 ]:
1.68g/cm3

[ 沸点 ]:
486.1ºC at 760 mmHg

[ 分子式 ]:
C₇H₉N₅O

[ 分子量 ]:
179.17900

[ 闪点 ]:
247.8ºC

[ 精确质量 ]:
179.08100

[ PSA ]:
89.59000

[ LogP ]:
0.30290

[ 折射率 ]:
1.798

[ 储存条件 ]:
2-8°C

9-乙基鸟嘌呤MSDS

9-乙基鸟嘌呤安全信息

[ 安全声明 (欧洲) ]:
24/25

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

[ 海关编码 ]:
2933990090

9-乙基鸟嘌呤合成路线

9-乙基鸟嘌呤上下游产品

9-乙基鸟嘌呤上游产品

9-乙基鸟嘌呤下游产品

9-乙基鸟嘌呤海关

[ 海关编码 ]: 2933990090

[ 中文概述 ]:
2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

9-乙基鸟嘌呤文献

Protein ruthenation and DNA alkylation: chlorambucil-functionalized RAPTA complexes and their anticancer activity.

Dalton Trans. 44(8) , 3614-23, (2015)

Chemotherapeutics for the treatment of tumorigenic conditions that feature novel modes of action are highly sought after to overcome the limitations of current chemotherapies. Herein, we report the co...

Organometallic anticancer complexes of lapachol: metal centre-dependent formation of reactive oxygen species and correlation with cytotoxicity.

Chem. Commun. (Camb.) 49(32) , 3348-50, (2013)

Organometallic Ru(II), Os(II) and Rh(III) complexes of lapachol induce apoptosis in human tumour cell lines in the low μM range by a mode of action involving oxidative stress, especially in the case o...

Amide linkage isomerism as an activity switch for organometallic osmium and ruthenium anticancer complexes.

J. Med. Chem. 52(23) , 7753-64, (2009)

We show that the binding mode adopted by picolinamide derivatives in organometallic Os(II) and Ru(II) half-sandwich complexes can lead to contrasting cancer cell cytotoxicity. N-Phenyl picolinamide de...

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